Market Cap 6.20B
Revenue (ttm) 46.02M
Net Income (ttm) -130.15M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE 92.61
Profit Margin -282.81%
Debt to Equity Ratio 0.00
Volume 2,029,200
Avg Vol 801,848
Day's Range N/A - N/A
Shares Out 63.81M
Stochastic %K 55%
Beta 2.23
Analysts Strong Sell
Price Target $105.50

Company Profile

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is al...

Industry: Biotechnology
Sector: Healthcare
Phone: 510 474 0170
Address:
7707 Gateway Boulevard, Suite 140, Newark, United States
Cache_Money
Cache_Money Mar. 19 at 10:22 PM
$PTGX I believe we’ll see more accumulation in the coming weeks. An interesting thing to note about this stock is that it has not had great visibility for retail - most of the interest has been from institutions.
0 · Reply
TheWolfOfSanFran
TheWolfOfSanFran Mar. 19 at 7:01 PM
$PTGX to the moon 🌙 with $JNJ
0 · Reply
erevnon
erevnon Mar. 19 at 4:32 PM
Citigroup maintains Protagonist Therapeutics $PTGX at Buy and raises the price target from $115 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
Cache_Money
Cache_Money Mar. 19 at 3:25 PM
$PTGX Liftoff!
0 · Reply
Jonita
Jonita Mar. 19 at 1:34 PM
$PTGX 💣💣💣
0 · Reply
NorthStarStats
NorthStarStats Mar. 19 at 2:01 AM
Output from a custom NorthStarStats momentum scanner highlighting stocks with strengthening price structure and momentum. Setups to watch and study — not trade recommendations. Brutal Scores: $PTGX Score: 73, $DAY Score: 70, $CNTA Score: 70, $MU Score: 63, $CTRA Score: 58
0 · Reply
mikesterz7
mikesterz7 Mar. 18 at 8:24 PM
$PTGX The FDA approved the drug for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age and older on Wednesday.
0 · Reply
StocktwitsNews
StocktwitsNews Mar. 18 at 8:12 PM
Wall Street Says Johnson And Johnson’s FDA-Approved Psoriasis Drug Should Create 'Significant Value’ For Protagonist Therapeutics $PTGX $JNJ https://stocktwits.com/news/equity/markets/wall-street-says-johnson-and-johnson-fda-approved-psoriasis-drug-should-create-significant-value-for-protagonist-therapeutics/cZ37nDaRIWE
0 · Reply
Quantumup
Quantumup Mar. 18 at 2:40 PM
Truist reiterated $PTGX Buy; $110, $JNJ $ABVX $ALMS ABBV $TAK Truist said:::This morning, Protagonist (PTGX, Buy) and Johnson & Johnson (JNJ, NR) reported FDA approval of Icotyde (icotrokinra) in 12+ year old moderate to severe plaque psoriasis (PsO), marking Protagonist's official transition to a commercial company. We see strong differentiation as the first oral therapy with biologic-like efficacy in a TAM with ~8M patients, as per JNJ. We model $730M peak revenue to PTGX in royalties vs $560M consensus and note partner JNJ (JNJ, NR) estimates ico to present a~$5-10B market opportunity. With priority review for rusfertide (launch expected 2H26), we think this sets PTGX up to continue to deliver pipeline progress with strong cash position. Reiterate Buy.
1 · Reply
outlawinvestor1
outlawinvestor1 Mar. 18 at 12:30 PM
$PTGX $50M milestone payment triggered by FDA approval. Protagonist is eligible to receive 6 - 10% royalties on sales and up to $580M in milestone payments. https://www.jnj.com/media-center/press-releases/fda-approval-of-icotyde-icotrokinra-ushers-in-new-era-for-first-line-systemic-treatment-of-plaque-psoriasis-with-a-targeted-oral-peptide
0 · Reply
Latest News on PTGX
RTW Investments' Rod Wong: Expect more deals in biotech space

Oct 10, 2025, 1:21 PM EDT - 5 months ago

RTW Investments' Rod Wong: Expect more deals in biotech space

JNJ XBI


Johnson & Johnson in Talks to Buy Protagonist Therapeutics

Oct 10, 2025, 11:13 AM EDT - 5 months ago

Johnson & Johnson in Talks to Buy Protagonist Therapeutics

JNJ


Protagonist Therapeutics Reports Granting of Inducement Award

Apr 16, 2025, 4:05 PM EDT - 1 year ago

Protagonist Therapeutics Reports Granting of Inducement Award


Overlooked Stock: PTGX

Mar 10, 2025, 4:57 PM EDT - 1 year ago

Overlooked Stock: PTGX


Why Is Protagonist Therapeutics Stock Trading Higher On Monday?

Mar 10, 2025, 10:04 AM EDT - 1 year ago

Why Is Protagonist Therapeutics Stock Trading Higher On Monday?


Cache_Money
Cache_Money Mar. 19 at 10:22 PM
$PTGX I believe we’ll see more accumulation in the coming weeks. An interesting thing to note about this stock is that it has not had great visibility for retail - most of the interest has been from institutions.
0 · Reply
TheWolfOfSanFran
TheWolfOfSanFran Mar. 19 at 7:01 PM
$PTGX to the moon 🌙 with $JNJ
0 · Reply
erevnon
erevnon Mar. 19 at 4:32 PM
Citigroup maintains Protagonist Therapeutics $PTGX at Buy and raises the price target from $115 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
Cache_Money
Cache_Money Mar. 19 at 3:25 PM
$PTGX Liftoff!
0 · Reply
Jonita
Jonita Mar. 19 at 1:34 PM
$PTGX 💣💣💣
0 · Reply
NorthStarStats
NorthStarStats Mar. 19 at 2:01 AM
Output from a custom NorthStarStats momentum scanner highlighting stocks with strengthening price structure and momentum. Setups to watch and study — not trade recommendations. Brutal Scores: $PTGX Score: 73, $DAY Score: 70, $CNTA Score: 70, $MU Score: 63, $CTRA Score: 58
0 · Reply
mikesterz7
mikesterz7 Mar. 18 at 8:24 PM
$PTGX The FDA approved the drug for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age and older on Wednesday.
0 · Reply
StocktwitsNews
StocktwitsNews Mar. 18 at 8:12 PM
Wall Street Says Johnson And Johnson’s FDA-Approved Psoriasis Drug Should Create 'Significant Value’ For Protagonist Therapeutics $PTGX $JNJ https://stocktwits.com/news/equity/markets/wall-street-says-johnson-and-johnson-fda-approved-psoriasis-drug-should-create-significant-value-for-protagonist-therapeutics/cZ37nDaRIWE
0 · Reply
Quantumup
Quantumup Mar. 18 at 2:40 PM
Truist reiterated $PTGX Buy; $110, $JNJ $ABVX $ALMS ABBV $TAK Truist said:::This morning, Protagonist (PTGX, Buy) and Johnson & Johnson (JNJ, NR) reported FDA approval of Icotyde (icotrokinra) in 12+ year old moderate to severe plaque psoriasis (PsO), marking Protagonist's official transition to a commercial company. We see strong differentiation as the first oral therapy with biologic-like efficacy in a TAM with ~8M patients, as per JNJ. We model $730M peak revenue to PTGX in royalties vs $560M consensus and note partner JNJ (JNJ, NR) estimates ico to present a~$5-10B market opportunity. With priority review for rusfertide (launch expected 2H26), we think this sets PTGX up to continue to deliver pipeline progress with strong cash position. Reiterate Buy.
1 · Reply
outlawinvestor1
outlawinvestor1 Mar. 18 at 12:30 PM
$PTGX $50M milestone payment triggered by FDA approval. Protagonist is eligible to receive 6 - 10% royalties on sales and up to $580M in milestone payments. https://www.jnj.com/media-center/press-releases/fda-approval-of-icotyde-icotrokinra-ushers-in-new-era-for-first-line-systemic-treatment-of-plaque-psoriasis-with-a-targeted-oral-peptide
0 · Reply
Jonita
Jonita Mar. 18 at 12:20 PM
$PTGX 💣💣💣💣
0 · Reply
Stock_Catcher
Stock_Catcher Mar. 18 at 12:06 PM
$PTGX ​​PTGX Protagonist Therapeutics Announces U.S. FDA Approval of ICOTYDE(TM) (icotrokinra) for the Treatment of Moderate to Severe Plaque Psoriasis
0 · Reply
Quantumup
Quantumup Mar. 17 at 2:11 PM
Piper Sandler reiterated $ABVX Overweight; $165, and said:::Framing Our Outlook Ahead of P3 ABTECT Maintenance Data $AZN $LLY ABBV PFE $JNJ - $PTGX Piper Sandler added:::Remain OW rated on ABVX as we outline herein our latest thoughts on the stock setup into P3 UC maintenance data (June) and the rest of the year. Outside of recent news flow around a potential ABVX takeout, we have fielded a growing number of investor inbounds around expectations for UC maintenance. To put it simply, we believe the P3 UC induction data, body of long-term P2b data, and ABTECT trial design elements have largely de-risked the readout, and believe the company's bar for success (20-30% pbo-adjusted clinical remission) is highly achievable and likely conservative. We continue to see the risk/ reward as attractive, and remain buyers.
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Quantumup
Quantumup Mar. 16 at 11:16 AM
Jefferies🏁 $ABVX at a Buy rating and a $160 PT. $AZN $LLY ABBV PFE $PTGX - $JNJ Jefferies said in its initiation report: Obe already looks like a real and differentiated UC drug, and we think the 2Q26 maintenance readout is fairly de-risked and should provide clear path to approval. We also think Crohn's matters for the long-term valuation (and hence any potl strategic interest). We are more bullish vs buyside expectations and see a strong shot based on MOA, translational data, and precedent. Bottom line: ABVX still underappreciated relative to the robust UC story and CD upside.
0 · Reply
Quantumup
Quantumup Mar. 13 at 1:15 PM
Stifel⬆️ $ORKA's PT to $72 from $47 and reitertaed at Buy. $ABBV $JNJ - $PTGX $UCBJY Stifel said—ORKA now expects Ph2 psoriasis data from ORKA-001 in 2Q26 (from 2H26) -- enrollment completed December 2025. ORKA plans to share week-16 data while providing longer-term follow-up in 2H26 -- the prior guidance was to share both together. Bottom line, this update significantly moves up the timing of ORKA's first clinical readout, and we expect to see shares react favorably towards increased proximity to the update. In terms of bar for success, we think PASI100 rates in-line with Skyrizi (36-51%) would represent a win with potential for Q6M or yearly vs. Q3M dosing while we see prospective support for the exposure hypothesis from the KNOCKOUT study providing additional support for the upside hypothesis of Bimzelx-like responses (59%-68%). We see Base Case upside in the $50-$70 range; downside for inferior efficacy could see shares trade to $10-20 with a refocus towards ORKA-002.
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Quantumup
Quantumup Mar. 10 at 8:15 PM
Raymond James🏁 $ALMS $JNJ - $PTGX $BMY Raymond James Said—Initiating coverage of ALMS shares with a Strong Buy rating, $46 price target in that we think lead asset envudeucitinib (envu) — a next generation, more potent TYK2 inhibitor — is well positioned to take meaningful share in the massive and growing market for non-biologic options in moderate-to-severe plaque psoriasis (PsO). As we detail herein, while the market seems to assume Johnson & Johnson's (JNJ) icotrokinra (oral IL-23 inhibitor) is the heir apparent in this field, we think envu's emerging profile is likely to offer enough differentiation to compete head-to-head, while also changing the narrative around TYK2 inhibition after a disappointing launch for Bristol-Myers' (BMY) Sotyktu. We would be buyers in front of full data at this year's AAD (March 27-31) and for what we anticipate will be a launch that meaningfully exceeds investor expectations.
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erevnon
erevnon Mar. 3 at 4:19 PM
Goldman Sachs maintains Protagonist Therapeutics $PTGX at Neutral and raises the price target from $65 to https://marketsblock.com/stock-upgrades-and-downgrades/
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OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 26 at 8:06 PM
$PTGX RSI: 73.34, MACD: 0.7652 Vol: 2.26, MA20: 83.66, MA50: 84.58 ⚪ HOLD - Sideways 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
erevnon
erevnon Feb. 26 at 4:08 PM
Barclays maintains Protagonist Therapeutics $PTGX at Overweight and raises the price target from $108 to https://marketsblock.com/stock-upgrades-and-downgrades/
0 · Reply
Quantumup
Quantumup Feb. 24 at 9:24 PM
Stifel🏁 $ALMS and said, We are initiating coverage with a Buy Rating and $44 Target Price on Alumis Inc. (ALMS). $TAK $BMY $JNJ - $PTGX NVS ABBV Stifel added, Our positive thesis on the stock is predicated on our view that next-generation TYK2s with the ability to achieve full target coverage have the potential to grow into an important oral class with the benefit of no Boxed Warning. To that end, topline data in Psoriasis from ALMS' Envudeucitinib provides support for the target coverage thesis with data that looks superior to both Zasocitinib and Sotyktu—more details likely to come at AAD (3/27-3/31). Ultimately, success here derisks broader development not only in SLE (data 3Q26) but also in the plethora of other diseases where there's clear support for the TYK2 target/coverage hypothesis. Looking ahead, with an NDA filing on track in psoriasis in 2H26, we see a path towards a strategic transaction to support the launch and expansion of the TYK2+ pipeline.
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biochirp
biochirp Feb. 23 at 7:13 PM
$PTGX J&J just submit the 150$/share offer…
0 · Reply
BillionerOfKing
BillionerOfKing Feb. 22 at 6:24 PM
$PTGX Current Stock Price: $82.84 Contracts to trade: $85.0 PTGX Mar 20 2026 Call Entry: $2.60 Exit: $3.26 ROI: 25% Hold ~29 days Shared as daily free alerts and for educational purposes only. https://dailypickai.com/freealerts
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