Aug. 18 at 2:39 PM
$TTOO
AI Info
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FYI: platforms like the T2Lyme panel become less practical and significantly less effective as time passes, completely losing their edge to standard serology (antibody testing)
Efficiency Shifts
(First Few Weeks): Direct DNA detection shines. Standard serology (ELISA/Western Blot or Modified Two-Tier Testing) suffers from a diagnostic blind spot during the first 2–4 weeks because the body takes time to mount an antibody response . In this window, direct DNA detection offers high specificity before antibodies mature. (T2 importance) Patient avoids long term effects
(After a Few Months): The dynamic reverses. Borrelia burgdorferi does not linger in high volumes in the bloodstream. It rapidly leaves the vascular space to hide in deep tissues—such as (joints), (nerves), and skin. Transient (bacteria circulating in whole blood) drops off significantly. DNA assays face severe target-scarcity issues, high false-negative rates in late-stages.