Market Cap 147.65M
Revenue (ttm) 66.80M
Net Income (ttm) 8.57M
EPS (ttm) N/A
PE Ratio 21.33
Forward PE N/A
Profit Margin 12.83%
Debt to Equity Ratio 0.00
Volume 674,400
Avg Vol 406,596
Day's Range N/A - N/A
Shares Out 57.90M
Stochastic %K 50%
Beta 1.43
Analysts Sell
Price Target $4.50

Company Profile

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 242 1600
Address:
675 Massachusetts Avenue, 14th Floor, Cambridge, United States
Biodiad
Biodiad May. 13 at 10:47 PM
$SPRO The only thing they need the extra shares for is to buy another asset. I think they are doing that in conjunction with GSK with a similar deal to tebi. Spero maintains its cash runway guidance into 2028.
0 · Reply
mdboss
mdboss May. 13 at 8:47 PM
$SPRO Tebi is the mother load! I’m here for the BIG payday!
1 · Reply
Biodiad
Biodiad May. 13 at 8:44 PM
$SPRO Looking ahead, we are positioning the company for the next phase by advancing other corporate activities, including exploring opportunities to grow our portfolio of clinical-stage product candidates.”
0 · Reply
sadie444
sadie444 May. 13 at 8:25 PM
$SPRO So, no updates at all, in regard to the request for additional shares, and no indication other than the boilerplate language as to the path ahead for the organization post the PDUFA. Very annoyed with this Board for their lack of clarity in regard to the massive increase in share requests, especially in light of the fact that they have mothballed all the clinical trials other than Teb. I think we are looking at a payout here post approval, but because of the mixed messages being provided via their request for additional shares, they’re causing a great deal of angst for us to shareholders.
1 · Reply
GardnerJ
GardnerJ May. 13 at 8:21 PM
$SPRO pretty boring 🥱 report with boilerplate exploration language.
0 · Reply
sadie444
sadie444 May. 13 at 7:00 PM
$SPRO Once again, there is no conference call scheduled to coincide with the earnings release later today. I’m tired of not being able to get investor questions answered by this Board of Directors. They better provide more info regarding the requested increase in shares as well as information regarding the plan for royalties. This is not how a company should operate when it comes to investor relations!
1 · Reply
zerodayrounder
zerodayrounder May. 13 at 6:08 PM
$SPRO my guess is SPRO board wants to get one last equity award for the June cycle and hand off SPRO cash shell to reverse merger target in the September time frame. Hopefully that means SPRO gets the ball rolling on tebi asset sale today at least as it seems there is a gating factor here re 30 day HSR review; June 18 PDUFA and June 23 SPRO AGM. I would think shareholders would need to know of the tebi asset sale completed an HSR review (and FDA approved) before authorizing 120 million new shares. Seems like timing is becoming a tenuous situation for all involved.
3 · Reply
zerodayrounder
zerodayrounder May. 13 at 12:58 AM
File under: interesting $SPRO $GSK Immunitas platform validated? IMT-009 not a lead asset and not really related to GSK core areas of anti infectives and oncology Boehringer makes €407M bet on Immunitas’ inflammatory asset https://www.fiercebiotech.com/biotech/boehringer-furthers-inflammatory-expansion-eu407m-biobuck-bet-immunitas-asset
1 · Reply
DDel
DDel May. 12 at 6:28 PM
0 · Reply
zerodayrounder
zerodayrounder May. 12 at 4:35 PM
At least Ryan Cohen $GME actually disclosed what they planned to use 2.5 billion extra shares on $EBAY $SPRO has got some 'splainin to do for the 120 million extra authorized shares they are requesting on June 23. 30-day HSR from May 15 gives about a week separation from June 23 AGM ... IF ... the share authorization is tied to a tebi asset sale. https://www.bamsec.com/filing/119312526217168?cik=1326380
0 · Reply
Latest News on SPRO
Spero Therapeutics Earnings Call Transcript: Q2 2025

Aug 12, 2025, 4:30 PM EDT - 9 months ago

Spero Therapeutics Earnings Call Transcript: Q2 2025


Spero Therapeutics Earnings Call Transcript: Q4 2024

Mar 27, 2025, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings Call Transcript: Q4 2024


Spero Therapeutics reports Q4 EPS (38c), consensus (31c)

2025-03-27T20:20:55.000Z - 1 year ago

Spero Therapeutics reports Q4 EPS (38c), consensus (31c)


Spero Therapeutics announces interim leadership changes

2025-01-10T12:31:40.000Z - 1 year ago

Spero Therapeutics announces interim leadership changes


Spero Therapeutics downgraded to Hold from Buy at TD Cowen

2024-11-18T12:41:28.000Z - 1 year ago

Spero Therapeutics downgraded to Hold from Buy at TD Cowen


Spero Therapeutics reports Q3 EPS (32c), consensus (36c)

2024-11-14T21:20:42.000Z - 1 year ago

Spero Therapeutics reports Q3 EPS (32c), consensus (36c)


Spero Therapeutics Earnings Call Transcript: Q2 2024

Aug 5, 2024, 4:30 PM EDT - 1 year ago

Spero Therapeutics Earnings Call Transcript: Q2 2024


Spero Therapeutics Earnings Call Transcript: Q4 2023

Mar 13, 2024, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q4 2023


Spero Therapeutics Provides Corporate Update and 2024 Outlook

Jan 5, 2024, 8:05 AM EST - 2 years ago

Spero Therapeutics Provides Corporate Update and 2024 Outlook


Spero Therapeutics Earnings Call Transcript: Q3 2023

Nov 13, 2023, 4:30 PM EST - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q3 2023


Spero Therapeutics Earnings Call Transcript: Q2 2023

Aug 10, 2023, 4:30 PM EDT - 2 years ago

Spero Therapeutics Earnings Call Transcript: Q2 2023


Spero Therapeutics Earnings Call Transcript: Q1 2023

May 11, 2023, 4:30 PM EDT - 3 years ago

Spero Therapeutics Earnings Call Transcript: Q1 2023


Spero Therapeutics to Present at Upcoming Investor Conference

Apr 26, 2023, 8:05 AM EDT - 3 years ago

Spero Therapeutics to Present at Upcoming Investor Conference


Biodiad
Biodiad May. 13 at 10:47 PM
$SPRO The only thing they need the extra shares for is to buy another asset. I think they are doing that in conjunction with GSK with a similar deal to tebi. Spero maintains its cash runway guidance into 2028.
0 · Reply
mdboss
mdboss May. 13 at 8:47 PM
$SPRO Tebi is the mother load! I’m here for the BIG payday!
1 · Reply
Biodiad
Biodiad May. 13 at 8:44 PM
$SPRO Looking ahead, we are positioning the company for the next phase by advancing other corporate activities, including exploring opportunities to grow our portfolio of clinical-stage product candidates.”
0 · Reply
sadie444
sadie444 May. 13 at 8:25 PM
$SPRO So, no updates at all, in regard to the request for additional shares, and no indication other than the boilerplate language as to the path ahead for the organization post the PDUFA. Very annoyed with this Board for their lack of clarity in regard to the massive increase in share requests, especially in light of the fact that they have mothballed all the clinical trials other than Teb. I think we are looking at a payout here post approval, but because of the mixed messages being provided via their request for additional shares, they’re causing a great deal of angst for us to shareholders.
1 · Reply
GardnerJ
GardnerJ May. 13 at 8:21 PM
$SPRO pretty boring 🥱 report with boilerplate exploration language.
0 · Reply
sadie444
sadie444 May. 13 at 7:00 PM
$SPRO Once again, there is no conference call scheduled to coincide with the earnings release later today. I’m tired of not being able to get investor questions answered by this Board of Directors. They better provide more info regarding the requested increase in shares as well as information regarding the plan for royalties. This is not how a company should operate when it comes to investor relations!
1 · Reply
zerodayrounder
zerodayrounder May. 13 at 6:08 PM
$SPRO my guess is SPRO board wants to get one last equity award for the June cycle and hand off SPRO cash shell to reverse merger target in the September time frame. Hopefully that means SPRO gets the ball rolling on tebi asset sale today at least as it seems there is a gating factor here re 30 day HSR review; June 18 PDUFA and June 23 SPRO AGM. I would think shareholders would need to know of the tebi asset sale completed an HSR review (and FDA approved) before authorizing 120 million new shares. Seems like timing is becoming a tenuous situation for all involved.
3 · Reply
zerodayrounder
zerodayrounder May. 13 at 12:58 AM
File under: interesting $SPRO $GSK Immunitas platform validated? IMT-009 not a lead asset and not really related to GSK core areas of anti infectives and oncology Boehringer makes €407M bet on Immunitas’ inflammatory asset https://www.fiercebiotech.com/biotech/boehringer-furthers-inflammatory-expansion-eu407m-biobuck-bet-immunitas-asset
1 · Reply
DDel
DDel May. 12 at 6:28 PM
0 · Reply
zerodayrounder
zerodayrounder May. 12 at 4:35 PM
At least Ryan Cohen $GME actually disclosed what they planned to use 2.5 billion extra shares on $EBAY $SPRO has got some 'splainin to do for the 120 million extra authorized shares they are requesting on June 23. 30-day HSR from May 15 gives about a week separation from June 23 AGM ... IF ... the share authorization is tied to a tebi asset sale. https://www.bamsec.com/filing/119312526217168?cik=1326380
0 · Reply
zerodayrounder
zerodayrounder May. 12 at 12:18 AM
0 · Reply
zerodayrounder
zerodayrounder May. 11 at 7:44 PM
$SPRO following $GSK lower. Maybe similar to the GSK move that began on Jan 15 and was final flush before RAPT and a move higher into Q4 report.
0 · Reply
CharlieeMungerTWITS
CharlieeMungerTWITS May. 11 at 9:59 AM
$SPRO “No leaks” arguments cut both ways. Real M&A often leaks through unusual options activity, abnormal volume, bankers/law firms entering, etc.
0 · Reply
zerodayrounder
zerodayrounder May. 11 at 3:14 AM
$SPRO $GSK one last thing, if GSK buys tebi it starts the 30 day HSR review this week and would conclude around June 15. The PDUFA is June 18. And the SPRO AGM is June 23. Also, if these hypothetical transactions (Tebi asset sale + reverse merger) were to be announced -- tomorrow -- they would be massively material subsequent events that would require significant footnotes in the 10Q that is due by May 15. I wonder if SPRO pushed back the Q1 report til Wednesday to give the accounting team and PwC auditors a little extra time to sign off on subsequent event disclosures. Waiting til May 18 is pushing the timelines super duper close IF these ideas are anywhere near reality. You also risk leaks if lots of parties are in the know on these transactions including auditors, lawyers, advisors, insiders etc etc
0 · Reply
zerodayrounder
zerodayrounder May. 10 at 2:29 PM
1 · Reply
zerodayrounder
zerodayrounder May. 9 at 6:42 PM
$SPRO $GSK hopefully the Barney's and the Limey's are working this weekend https://www.youtube.com/watch?v=gArnm_Uicsw
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zerodayrounder
zerodayrounder May. 9 at 12:26 AM
$GSK frenemy Shionogi (ViiV Healthcare JV partner; AMR challenger) reports on Tuesday in Japan. Shionogi rumored to be the buyer of $ITRM Orlynvah out of the liquidation proceedings (according to that group of internet sleuths). Perhaps GSK wants to front-run Shionogi by announcing acquisition of tebipenem rights and the reverse merger Tx's considered ad nauseum on my stream to set the narrative for oral carbapenems for cUTI as #1 player in AMR (as the GSK Chairman discussed at the AGM) while funding another shot on goal in oncology space. $SPRO Q1 earnings just becoms a date to report Q1 numbers and file 10-Q with the fireworks happening on Monday?
2 · Reply
Homepayment
Homepayment May. 8 at 7:33 PM
0 · Reply
zerodayrounder
zerodayrounder May. 8 at 6:06 PM
$SPRO it is only obvious, when it becomes obviously obvious "Allegedly"
0 · Reply
zerodayrounder
zerodayrounder May. 8 at 5:49 PM
$SPRO was trading about 250k per session in the 8-9 days leading up to March 26, 2026 Q4 report in a downtrend. We are doing about 500k avg over the last week or so and trying to turn up just over 9EMA and 50SMA. I don't think any accumulation has to do with a PDUFA date. The market would still look at SPRO as a royalty shell with uncertain cash flows and no control over its own destiny at all (along with GSK overhang/control). And high likelihood of misallocating royalty cash flows in a drug pipeline it has no experience or team set up to manage. The only solution is for GSK to back up its Chairman's claims about being #1 in AMR and acquiring full rights of tebipenem, then effecting a reverse merge into a promising Boston area biotech w/ great pipeline, team and a need for $$$ to fund Phase 2/3 clinical trials that GSK wants to invest in with its 16% SPRO equity. NewCO takes over SPRO nasdaq listing, brings in new management and replaces entire SPRO board. It is written.
1 · Reply
Inc82
Inc82 May. 8 at 5:22 PM
$SPRO accumulation?
0 · Reply
zerodayrounder
zerodayrounder May. 8 at 2:37 PM
$SPRO $GSK "let me tell you somethin', ya suspect, yeah you." 🫵 https://www.youtube.com/watch?v=OHSYWIAAY2o
0 · Reply