Aug. 13 at 10:30 PM
While emerging RAS-targeted therapies focus on inhibiting oncogenic signaling, Propanc's PRP is designed to operate differently: promoting cancer cell differentiation, reversing EMT, and targeting cancer stem cells associated with recurrence, resistance, and metastasis.
PRP is not mutation-specific, potentially positioning its non-cytotoxic, proenzyme-based mechanism as a complementary approach for aggressive solid tumors.
Recent preclinical PDAC data showed >90% mean tumor growth inhibition, reduced metastatic burden, and >2.5x extension of median overall survival versus controls.
Now, the focus moves to clinical execution. Propanc expects to file its Clinical Trial Application for the planned Phase 1b study in Q4 2026.
The next step: bringing PRP into the clinic.
$PPCB