Market Cap 95.78M
Revenue (ttm) 0.00
Net Income (ttm) -39.72M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 24,700
Avg Vol 43,496
Day's Range N/A - N/A
Shares Out 8.97M
Stochastic %K 54%
Beta -0.20
Analysts Strong Sell
Price Target $34.38

Company Profile

ProMIS Neurosciences, Inc. discovers and develops antibody therapies and therapeutic vaccines for neurodegenerative diseases and other misfolded protein diseases in Canada. The company's proprietary discovery platform comprises ProMIS, which enables drug discovery through a combination of protein biology, physics, and supercomputing. Its lead product candidates include PMN310, a monoclonal antibody (mAb) for toxic oligomers for treating Alzheimer's disease; PMN267 for the treatment of amyotrophi...

Industry: Biotechnology
Sector: Healthcare
Phone: 416 847 6898
Address:
1920 Yonge Street, Suite 200, Toronto, Canada
Blueknoser
Blueknoser May. 13 at 12:08 PM
$PMN https://d1io3yog0oux5.cloudfront.net/_900e463caf66de95205aaee95614d18d/promisneurosciences/db/933/8955/pdf/ProMIS_Investor+Presentation+2026.pdf
0 · Reply
benorr95
benorr95 May. 12 at 1:02 PM
$PMN tiny tape risk reward only gets interesting if volume confirms
1 · Reply
Blueknoser
Blueknoser May. 12 at 11:28 AM
$PMN "2026 has the potential to be a significant year for patients with Alzheimer's disease and their caregivers,” said Neil Warma, Chief Executive Officer of ProMIS Neurosciences. “We believe ProMIS is well-positioned with PMN310 as a potentially differentiated treatment for patients with early AD. We are coming off a productive quarter, having closed a transformational financing of up to $175 million, including potential proceeds from warrant exercises, and have executed well on our Phase 1b clinical trial. Near-term data catalysts, including the blinded 6-month interim analysis, are anticipated in early Q3 2026, and could provide important insight into the potential of our lead drug candidate, PMN310. With currently marketed AD therapies, safety remains a central concern. Both approved plaque-directed antibodies carry black box warnings for a serious side effect known as ARIA, which encompasses cerebral edema (ARIA-E) and microhemorrhages (ARIA-H) in the brain....."
0 · Reply
Blueknoser
Blueknoser May. 12 at 11:23 AM
$PMN https://www.promisneurosciences.com/investors/news-events/press-releases/detail/267/promis-neurosciences-announces-first-quarter-2026-financial
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focafoca99
focafoca99 May. 12 at 11:00 AM
$PMN has released its Q1 2026 financial results for the quarter ended March 31, 2026.
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Blueknoser
Blueknoser May. 11 at 5:05 PM
$PMN A quick search on insiders ownership: Insiders own approximately 28.97% to 31% of ProMIS Neurosciences (PMN) stock as of May 2026. This ownership represents about 2.59 million shares held by 19 identified insiders, with recent activity showing a trend of buying rather than selling among company leadership. Insider Buying Trend: There has been a notable pattern of insider purchases, such as acquisitions by Chief Development Officer Johanne Kaplan and other directors early in 2026.Institutional Ownership: Approximately 31.02% to 50.13% of the stock is held by institutional investors.Significant Holders: Ally Bridge Group (NY) LLC is listed as a major investor.The high level of insider ownership and buying activity is generally interpreted as a positive signal, suggesting alignment between company leadership and shareholders, according to Yahoo Finance.
1 · Reply
tonkotsu
tonkotsu May. 11 at 6:04 AM
$PMN Anyone know why there the executives/board don’t own more shares?
1 · Reply
Blueknoser
Blueknoser May. 8 at 10:34 AM
$PMN "This positions the ongoing PRECISE-AD study to potentially become the first clinical test of oligomer-only targeting, which may clarify the relative contributions of oligomers vs plaque to cognitive decline, an important scientific inflection point for the field." The Cochrane Study doesn't include PMN310 or its differentiated approach: it included 17 studies with 20,342 participants. The 17 studies assessed seven different amyloid‐beta‐targeting monoclonal antibodies: aducanumab, bapineuzumab, crenezumab, donanemab, gantenerumab, lecanemab, and solanezumab. PMN310: “This publication provides further evidence, supported experimentally and clinically, that selective targeting of toxic Aβ oligomers has the potential to increase efficacy by focusing the dose of antibody on the most relevant toxic Aβ species and improve safety by reducing the risk of ARIA associated with plaque binding which has been a significant side effect of current Aβ-directed antibodies,” said Johanne Kaplan, PhD
1 · Reply
Blueknoser
Blueknoser May. 7 at 2:16 PM
$PMN https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016297/full Differentiated approach: PMN310 A Potential Best-in-Class Therapy for Alzheimer’s Disease ProMIS’ lead therapeutic product candidate, PMN310, is a monoclonal therapeutic antibody designed for the treatment of Alzheimer’s disease (AD). By selectively targeting the toxic oligomers of amyloid-beta (Aβ), PMN310 may possess the qualities necessary to potentially be “best-in-class”, if approved, with a possibly more favorable clinical safety and efficacy profile over other amyloid-directed antibody therapeutics currently in clinical development. PMN310 was granted Fast Track Designation by U.S. FDA for treatment of Alzheimer’s disease last summer.
1 · Reply
Guestthatrader
Guestthatrader May. 7 at 8:35 AM
$PMAX $AIXI $PMN $BYND get in $UK its heating up just need volume 600k float
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Latest News on PMN
ProMIS Neurosciences files $200M mixed securities shelf

2026-03-25T21:25:26.000Z - 6 weeks ago

ProMIS Neurosciences files $200M mixed securities shelf


Promis Neurosciences Inc trading resumes

2026-01-30T14:40:46.000Z - 3 months ago

Promis Neurosciences Inc trading resumes


ProMIS Neurosciences exceeds target enrollment in PRECISE-AD

2025-12-18T12:36:07.000Z - 5 months ago

ProMIS Neurosciences exceeds target enrollment in PRECISE-AD


ProMIS Neurosciences announces publication highlighting PMN310

2025-12-10T12:45:11.000Z - 5 months ago

ProMIS Neurosciences announces publication highlighting PMN310


Promis Neurosciences Inc trading halted, news pending

2025-11-27T00:50:21.000Z - 5 months ago

Promis Neurosciences Inc trading halted, news pending


ProMIS Neurosciences announces 1-for-20 reverse stock split

2025-11-24T13:25:21.000Z - 6 months ago

ProMIS Neurosciences announces 1-for-20 reverse stock split


ProMIS Neurosciences Announces Reverse Stock Split

Nov 24, 2025, 8:00 AM EST - 6 months ago

ProMIS Neurosciences Announces Reverse Stock Split


ProMIS Neurosciences reports Q3 EPS (24c) vs 31c last year

2025-11-12T12:22:19.000Z - 6 months ago

ProMIS Neurosciences reports Q3 EPS (24c) vs 31c last year


ProMIS Neurosciences files $50M mixed securities shelf

2025-08-13T20:40:25.000Z - 9 months ago

ProMIS Neurosciences files $50M mixed securities shelf


ProMIS Neurosciences reports Q2 EPS (29c) vs (13c) last year

2025-08-13T11:12:40.000Z - 9 months ago

ProMIS Neurosciences reports Q2 EPS (29c) vs (13c) last year


ProMIS Neurosciences to present overview from PRECISE-AD trial

2025-07-29T12:22:34.000Z - 10 months ago

ProMIS Neurosciences to present overview from PRECISE-AD trial


ProMIS Neurosciences announces private placement financing

2025-07-28T11:10:27.000Z - 10 months ago

ProMIS Neurosciences announces private placement financing


ProMIS Neurosciences Announces Private Placement Financing

Jul 28, 2025, 7:00 AM EDT - 10 months ago

ProMIS Neurosciences Announces Private Placement Financing


ProMIS Neurosciences announces $0.8M registered direct offering

2025-07-22T11:22:47.000Z - 10 months ago

ProMIS Neurosciences announces $0.8M registered direct offering


ProMIS Neurosciences Issues Letter to Shareholders

Jan 13, 2025, 10:30 AM EST - 1 year ago

ProMIS Neurosciences Issues Letter to Shareholders


ProMIS Neurosciences, Inc. Announces Leadership Transition

Jan 3, 2024, 7:00 AM EST - 2 years ago

ProMIS Neurosciences, Inc. Announces Leadership Transition


Blueknoser
Blueknoser May. 13 at 12:08 PM
$PMN https://d1io3yog0oux5.cloudfront.net/_900e463caf66de95205aaee95614d18d/promisneurosciences/db/933/8955/pdf/ProMIS_Investor+Presentation+2026.pdf
0 · Reply
benorr95
benorr95 May. 12 at 1:02 PM
$PMN tiny tape risk reward only gets interesting if volume confirms
1 · Reply
Blueknoser
Blueknoser May. 12 at 11:28 AM
$PMN "2026 has the potential to be a significant year for patients with Alzheimer's disease and their caregivers,” said Neil Warma, Chief Executive Officer of ProMIS Neurosciences. “We believe ProMIS is well-positioned with PMN310 as a potentially differentiated treatment for patients with early AD. We are coming off a productive quarter, having closed a transformational financing of up to $175 million, including potential proceeds from warrant exercises, and have executed well on our Phase 1b clinical trial. Near-term data catalysts, including the blinded 6-month interim analysis, are anticipated in early Q3 2026, and could provide important insight into the potential of our lead drug candidate, PMN310. With currently marketed AD therapies, safety remains a central concern. Both approved plaque-directed antibodies carry black box warnings for a serious side effect known as ARIA, which encompasses cerebral edema (ARIA-E) and microhemorrhages (ARIA-H) in the brain....."
0 · Reply
Blueknoser
Blueknoser May. 12 at 11:23 AM
$PMN https://www.promisneurosciences.com/investors/news-events/press-releases/detail/267/promis-neurosciences-announces-first-quarter-2026-financial
0 · Reply
focafoca99
focafoca99 May. 12 at 11:00 AM
$PMN has released its Q1 2026 financial results for the quarter ended March 31, 2026.
0 · Reply
Blueknoser
Blueknoser May. 11 at 5:05 PM
$PMN A quick search on insiders ownership: Insiders own approximately 28.97% to 31% of ProMIS Neurosciences (PMN) stock as of May 2026. This ownership represents about 2.59 million shares held by 19 identified insiders, with recent activity showing a trend of buying rather than selling among company leadership. Insider Buying Trend: There has been a notable pattern of insider purchases, such as acquisitions by Chief Development Officer Johanne Kaplan and other directors early in 2026.Institutional Ownership: Approximately 31.02% to 50.13% of the stock is held by institutional investors.Significant Holders: Ally Bridge Group (NY) LLC is listed as a major investor.The high level of insider ownership and buying activity is generally interpreted as a positive signal, suggesting alignment between company leadership and shareholders, according to Yahoo Finance.
1 · Reply
tonkotsu
tonkotsu May. 11 at 6:04 AM
$PMN Anyone know why there the executives/board don’t own more shares?
1 · Reply
Blueknoser
Blueknoser May. 8 at 10:34 AM
$PMN "This positions the ongoing PRECISE-AD study to potentially become the first clinical test of oligomer-only targeting, which may clarify the relative contributions of oligomers vs plaque to cognitive decline, an important scientific inflection point for the field." The Cochrane Study doesn't include PMN310 or its differentiated approach: it included 17 studies with 20,342 participants. The 17 studies assessed seven different amyloid‐beta‐targeting monoclonal antibodies: aducanumab, bapineuzumab, crenezumab, donanemab, gantenerumab, lecanemab, and solanezumab. PMN310: “This publication provides further evidence, supported experimentally and clinically, that selective targeting of toxic Aβ oligomers has the potential to increase efficacy by focusing the dose of antibody on the most relevant toxic Aβ species and improve safety by reducing the risk of ARIA associated with plaque binding which has been a significant side effect of current Aβ-directed antibodies,” said Johanne Kaplan, PhD
1 · Reply
Blueknoser
Blueknoser May. 7 at 2:16 PM
$PMN https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016297/full Differentiated approach: PMN310 A Potential Best-in-Class Therapy for Alzheimer’s Disease ProMIS’ lead therapeutic product candidate, PMN310, is a monoclonal therapeutic antibody designed for the treatment of Alzheimer’s disease (AD). By selectively targeting the toxic oligomers of amyloid-beta (Aβ), PMN310 may possess the qualities necessary to potentially be “best-in-class”, if approved, with a possibly more favorable clinical safety and efficacy profile over other amyloid-directed antibody therapeutics currently in clinical development. PMN310 was granted Fast Track Designation by U.S. FDA for treatment of Alzheimer’s disease last summer.
1 · Reply
Guestthatrader
Guestthatrader May. 7 at 8:35 AM
$PMAX $AIXI $PMN $BYND get in $UK its heating up just need volume 600k float
0 · Reply
Blueknoser
Blueknoser May. 6 at 5:30 PM
$PMN someday in the near future, PMN is going to explode, which will be the ending for those manipulating this down.....JMHO!
0 · Reply
tonkotsu
tonkotsu May. 4 at 7:33 PM
$PMN Almost quadrupled my position now. Now about 5% of my portfolio. Will continue to increase my allocation if it remains here or preferably if it drops further.
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Biotech_Pharma_Investor
Biotech_Pharma_Investor Apr. 30 at 2:48 PM
$PMN Getting interesting at $11 going towards the Q3 readout. PIPE was at $10.77 with warrants at $14.4
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tonkotsu
tonkotsu Apr. 28 at 5:10 PM
$PMN Lol I lied. I’ve doubled my position recently around this price point.
1 · Reply
Misterx69
Misterx69 Apr. 28 at 3:13 PM
$PMN We've dropped from $25 a couple of times to $10.7. Let's hope the double-bottom rule holds true and it starts to rise again.
1 · Reply
Sewdot
Sewdot Apr. 28 at 2:07 PM
$PMN I've joined the party
1 · Reply
Blueknoser
Blueknoser Apr. 28 at 10:22 AM
$PMN In the latest presentation the CEO, Mr. Neil Warma, all but states that PMN 310 has better efficacy, no ARIA, than the 2 existing treatments on the market; the company would already have the initial data by now, it's working for all accounts and purposes! Interesting to note: the 2 companies sell approximately 6 billion/year of their inferior treatments!!
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Blueknoser
Blueknoser Apr. 28 at 8:09 AM
$PMN https://www.youtube.com/watch?v=MVAmeYMf_LY
1 · Reply
Stormvyre
Stormvyre Apr. 25 at 6:29 AM
$PMN Clinical Timeline: At the Bloom Burton & Co. Healthcare Investor Conference (April 21–22), CEO Neil Warma outlined the roadmap for PMN310 (their lead Alzheimer’s candidate):
1 · Reply
Blueknoser
Blueknoser Apr. 24 at 10:32 AM
$PMN insider's are still buying: https://www.promisneurosciences.com/investors/sec-filings##document-766-0001104659-26-047977-2
1 · Reply
Blueknoser
Blueknoser Apr. 23 at 8:22 PM
$PMN the current stock manipulation is to rid the retail investors of their shares; patience is a virtue as they say! A couple of months, even just weeks, there's going to be a watershed moment! Hang in there!!
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Cellsci
Cellsci Apr. 21 at 1:51 PM
0 · Reply