Jul. 2 at 10:20 PM
$GERN Why, Quantumkid, are you assuming that the IMpactMF trial has been going on such a long time due to patients' living longer? Are you sure, because it may have had to do with bureaucratic mishaps and slow recruiting. If you're using the delay, which you appear to be -- correct me if I'm wrong -- as fodder for the idea of an efficacy stop, you may be disappointed. Mistergern is interpreting certain numbers in a self-serving light, including those from IMbarkMF, a trial under a wholly different design. The rarity of efficacy stops in oncology trials is well known, so it's up to mistergern/Claude to prove a contrary thesis for IMpactMF, not the other way around. Below is Gemini on why an IDMC stop for efficacy for IMpactMF is wishful thinking and almost an impossibility; however, I'll end with saying that nobody knows what will happen, and it's up to the IDMC.
Gemini below in a few posts: