Jun. 30 at 12:35 AM
$CLDX Why Anti-KIT Depletion (Celldex) is Winning across all CSU Drugs: The Root Cause: Celldex Therapeutics’ barzolvolimab targets the KIT receptor (a protein required for mast cell survival and function).The "Mast Cell Reset": Instead of just blocking cell signals, Celldex's approach depletes the pathogenic mast cells altogether. Once they are cleared out, the body generates new, healthy mast cells, essentially "resetting" the immune system. This eliminates the source of the hives and angioedema rather than just trying to quiet them down.
