Market Cap 8.08B
Revenue (ttm) 638.50M
Net Income (ttm) -183.17M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -28.69%
Debt to Equity Ratio 1.33
Volume 849,300
Avg Vol 630,336
Day's Range N/A - N/A
Shares Out 51.15M
Stochastic %K 23%
Beta 0.43
Analysts Strong Sell
Price Target $222.15

Company Profile

Axsome Therapeutics, Inc., a biopharmaceutical company, develops and delivers novel therapies for the management of central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist, sigma-1 receptor agonist, aminoketone, and CYP2D6 inhibitor indicated for the treatment of major depressive disorder in adults; Sunosi (solriamfetol), a dopamine and norepinephrine reuptak...

Industry: Biotechnology
Sector: Healthcare
Phone: 212 332 3241
Fax: 212 320 0245
Address:
One World Trade Center, 29th Floor, New York, United States
ThinkVision
ThinkVision Mar. 21 at 8:38 PM
$SPRY $AXSM $ASTS $GSAT $RKLB (NASDAQ) — This isn’t a donation or a casino bet… it’s a once-in-a-lifetime setup 🧨 (currently $8/share Roth initiated Price Target $40) Only globally approved, needle-free EpiPen epinephrine alternative → protected through 2039 Millions face life-threatening anaphylaxis daily → this replaces the needle ~22M+ shares short / ~45–48% of float → extreme positioning + fuel 20+ days to cover → pressure builds if demand accelerates $72.2M year-one U.S. revenue → demand is real 22,500+ prescribers, ~50% repeat → refill engine starting 2026 = shift to renewals → compounding revenue begins $84.3M FY revenue + $28.1M Q4 → acceleration underway Global rollout: EU, China, Australia → Canada next ~90% real-world success (single dose) → clinically validated 9,000+ schools onboarded → embedded distribution channel $0 copay + expanding coverage → unlocking mass adoption DTC + direct access → removing friction, scaling fast Sales force expanding → deeper penetration in 2026 $245M cash → runway to breakeven Urticaria pipeline → platform upside ALK partnership → global scale leverage Full details: https://www.globenewswire.com/news-release/2026/03/09/3251623/0/en/ARS-Pharmaceuticals-Reports-Fourth-Quarter-and-Full-Year-2025-Financial-Results-and-Updates-on-neffy-epinephrine-nasal-spray-Commercialization.html Learn more about neffy: http://neffy.com/about/ Global partner (ALK): http://alk.net/our-solutions Bottom line: De-risked, commercial-stage biotech with scaling adoption, global tailwinds, and a compounding revenue model 🔥
0 · Reply
TalkMarkets
TalkMarkets Mar. 21 at 1:48 AM
Healthcare Sector Review : Q1 2026 Cutbacks In Government Spending Are Taking Its Toll $ABOS $ABT $AXSM $BBIO $BDX https://talkmarkets.com/article/healthcare-sector-review-q1-2026-cutbacks-in-government-spending-are-taking-its-toll-1774057180
0 · Reply
A_Train1
A_Train1 Mar. 20 at 4:33 PM
$AXSM Why weakness here? On the verge of something great. Maybe triple-witching. But after today, do we begin to find a solid base? Or is healthcare/bios about due for a rotation out since XBI is at 5 year highs?
3 · Reply
Mike826_1999
Mike826_1999 Mar. 20 at 2:19 PM
$AXSM Axsome: Auvelity for major depressive disorder Weekly TRx grew +3% w/w to 17,200, +31% Y/Y, and rolling 12-wk +35% Y/Y New prescriptions (NRx) / TRx were 58% for the week
5 · Reply
kvn8533
kvn8533 Mar. 20 at 10:41 AM
$AXSM Strange premarket volume. Either option expiration or news coming later this AM
1 · Reply
Pjdevx
Pjdevx Mar. 19 at 8:40 PM
$CADL $AXSM Follow the revenue of AXSM and market cap. CADL will have 600M of revenue in a year and 6B market cap. Hold and be patient.
0 · Reply
JeffTex
JeffTex Mar. 19 at 2:53 PM
$AXSM when I mentioned months ago about only thing that worried me was our country holding together before we crossed the finish line on 05. We knew a lot of people were going to lose health ins was bad enough. But big double whammy with us in Iran & inadvertently helping Russia against our own interests. Doesn’t look good in a sense. Hopefully we pull thru it all
2 · Reply
11thestate
11thestate Mar. 19 at 2:23 PM
With everything going on around $AXSM lately — this is the info you don't want to miss: https://11th.com/cases/axsome-investor-settlement
1 · Reply
Morgan96
Morgan96 Mar. 18 at 10:14 PM
$AXSM Most people on these boards (both bulls and bears) are married to their positions. At a 3x revenue potential, the stock is richly priced without Alzheimer's Agitation approval. Sunosi is a fair revenue multiplier but migraine isn't moving the needle. The jury is out on the other drugs. The revenue projections provided by the company may be way too high. Regardless, an $8B market cap indicates a successful company. And I have been long for years.
0 · Reply
JeffTex
JeffTex Mar. 18 at 8:43 PM
$AXSM Dang $30+ down since great ER. Never thought we would drop back this much
3 · Reply
Latest News on AXSM
Axsome Therapeutics: A Conditional Buy Built On SG&A Discipline

Jan 24, 2026, 6:38 AM EST - 2 months ago

Axsome Therapeutics: A Conditional Buy Built On SG&A Discipline


MoneyShow's Best Investment Ideas For 2026: Part 2

Jan 12, 2026, 4:20 PM EST - 2 months ago

MoneyShow's Best Investment Ideas For 2026: Part 2

BDX BRO BX CALM


FDA Fast-Tracks Axsome's Alzheimer's Agitation Drug, Stock Soars

Dec 31, 2025, 10:30 AM EST - 2 months ago

FDA Fast-Tracks Axsome's Alzheimer's Agitation Drug, Stock Soars


Axsome: Some Recent Setbacks, Some Recent Wins -- Still A Buy

Jul 25, 2025, 1:46 PM EDT - 8 months ago

Axsome: Some Recent Setbacks, Some Recent Wins -- Still A Buy


Axsome Therapeutics, Inc. (AXSM) Q1 2025 Earnings Call Transcript

May 5, 2025, 11:44 AM EDT - 11 months ago

Axsome Therapeutics, Inc. (AXSM) Q1 2025 Earnings Call Transcript


Axsome Therapeutics Clocks Around 60% Topline Growth In Q1

May 5, 2025, 10:41 AM EDT - 11 months ago

Axsome Therapeutics Clocks Around 60% Topline Growth In Q1


Axsome: The Alzheimer's Agitation Program For AXS-05

Mar 21, 2025, 11:36 AM EDT - 1 year ago

Axsome: The Alzheimer's Agitation Program For AXS-05


Axsome Q4 Earnings: Revenues Rising, Skepticism Lingering

Feb 20, 2025, 8:15 AM EST - 1 year ago

Axsome Q4 Earnings: Revenues Rising, Skepticism Lingering


ThinkVision
ThinkVision Mar. 21 at 8:38 PM
$SPRY $AXSM $ASTS $GSAT $RKLB (NASDAQ) — This isn’t a donation or a casino bet… it’s a once-in-a-lifetime setup 🧨 (currently $8/share Roth initiated Price Target $40) Only globally approved, needle-free EpiPen epinephrine alternative → protected through 2039 Millions face life-threatening anaphylaxis daily → this replaces the needle ~22M+ shares short / ~45–48% of float → extreme positioning + fuel 20+ days to cover → pressure builds if demand accelerates $72.2M year-one U.S. revenue → demand is real 22,500+ prescribers, ~50% repeat → refill engine starting 2026 = shift to renewals → compounding revenue begins $84.3M FY revenue + $28.1M Q4 → acceleration underway Global rollout: EU, China, Australia → Canada next ~90% real-world success (single dose) → clinically validated 9,000+ schools onboarded → embedded distribution channel $0 copay + expanding coverage → unlocking mass adoption DTC + direct access → removing friction, scaling fast Sales force expanding → deeper penetration in 2026 $245M cash → runway to breakeven Urticaria pipeline → platform upside ALK partnership → global scale leverage Full details: https://www.globenewswire.com/news-release/2026/03/09/3251623/0/en/ARS-Pharmaceuticals-Reports-Fourth-Quarter-and-Full-Year-2025-Financial-Results-and-Updates-on-neffy-epinephrine-nasal-spray-Commercialization.html Learn more about neffy: http://neffy.com/about/ Global partner (ALK): http://alk.net/our-solutions Bottom line: De-risked, commercial-stage biotech with scaling adoption, global tailwinds, and a compounding revenue model 🔥
0 · Reply
TalkMarkets
TalkMarkets Mar. 21 at 1:48 AM
Healthcare Sector Review : Q1 2026 Cutbacks In Government Spending Are Taking Its Toll $ABOS $ABT $AXSM $BBIO $BDX https://talkmarkets.com/article/healthcare-sector-review-q1-2026-cutbacks-in-government-spending-are-taking-its-toll-1774057180
0 · Reply
A_Train1
A_Train1 Mar. 20 at 4:33 PM
$AXSM Why weakness here? On the verge of something great. Maybe triple-witching. But after today, do we begin to find a solid base? Or is healthcare/bios about due for a rotation out since XBI is at 5 year highs?
3 · Reply
Mike826_1999
Mike826_1999 Mar. 20 at 2:19 PM
$AXSM Axsome: Auvelity for major depressive disorder Weekly TRx grew +3% w/w to 17,200, +31% Y/Y, and rolling 12-wk +35% Y/Y New prescriptions (NRx) / TRx were 58% for the week
5 · Reply
kvn8533
kvn8533 Mar. 20 at 10:41 AM
$AXSM Strange premarket volume. Either option expiration or news coming later this AM
1 · Reply
Pjdevx
Pjdevx Mar. 19 at 8:40 PM
$CADL $AXSM Follow the revenue of AXSM and market cap. CADL will have 600M of revenue in a year and 6B market cap. Hold and be patient.
0 · Reply
JeffTex
JeffTex Mar. 19 at 2:53 PM
$AXSM when I mentioned months ago about only thing that worried me was our country holding together before we crossed the finish line on 05. We knew a lot of people were going to lose health ins was bad enough. But big double whammy with us in Iran & inadvertently helping Russia against our own interests. Doesn’t look good in a sense. Hopefully we pull thru it all
2 · Reply
11thestate
11thestate Mar. 19 at 2:23 PM
With everything going on around $AXSM lately — this is the info you don't want to miss: https://11th.com/cases/axsome-investor-settlement
1 · Reply
Morgan96
Morgan96 Mar. 18 at 10:14 PM
$AXSM Most people on these boards (both bulls and bears) are married to their positions. At a 3x revenue potential, the stock is richly priced without Alzheimer's Agitation approval. Sunosi is a fair revenue multiplier but migraine isn't moving the needle. The jury is out on the other drugs. The revenue projections provided by the company may be way too high. Regardless, an $8B market cap indicates a successful company. And I have been long for years.
0 · Reply
JeffTex
JeffTex Mar. 18 at 8:43 PM
$AXSM Dang $30+ down since great ER. Never thought we would drop back this much
3 · Reply
Live2ride
Live2ride Mar. 18 at 4:08 PM
$AXSM Just curious, are most here expecting a pre-pdufa run up in April? I'm certainly hoping for it but not sure what to expect. Wondering if pressure from the options market might hold us down. There is an unusually large number of open May 140 puts sitting out there. Just a hedge I guess.
3 · Reply
Willdowdell
Willdowdell Mar. 18 at 2:36 PM
$AXSM so what happens here if the agitation drug gets delayed/not approved? How much further does this fall?
2 · Reply
JuggernautRaider
JuggernautRaider Mar. 18 at 4:43 AM
$TNXP $AXSM if you push ChatGPT for the closest analog to what Tonix is doing, it’s Axsome - which had a fibromyalgia setback last year while Tonix was advancing to market. Just ask it yourself. The CNS pipeline similarities make so much sense and nobody believed in Axsome a few years ago (now it is a likely buyout candidate) 🏦 FYI: if you bought Axsome 5-6 years ago you made 40x. It’s a realistic outcome for Tonix investors: 5-10x seems guaranteed once the market catchs up with us 🤫
0 · Reply
Mike826_1999
Mike826_1999 Mar. 17 at 12:17 AM
$AXSM Interesting insight from investing friend BB: Rexulti from Otsuka is expected to face generic competition in 2028. If Auvelity receives approval for ADA, it’s possible we could see an ex-US deal with Otsuka for the Asian rights to Auvelity. Otsuka’s salesforce could push Auvelity for moderate MDD and ADA, saving Rexulti for severe symptoms, then potentially transition many of those customers to Auvelity for both MDD and ADA, just prior to the generics arrival. Such a deal might also include Otsuka sharing valuable clinical data from Otuska's DM trials for other indications, which could be highly beneficial for AXSM.
2 · Reply
All_just_a_game
All_just_a_game Mar. 16 at 6:38 PM
$AXSM I don’t know about you guys but I been seeing Auvelity ads all over all my streaming ad supported services. Alzheimer’s agitation launch and the sales force going to —-> 600 will accelerate sales…and OPEX but hopefully revenue growth outpaces opex growth.
3 · Reply
JuggernautRaider
JuggernautRaider Mar. 16 at 12:55 PM
$TNXP I hope you spent your extra time this weekend looking for different ways to make cash to buy more shares of Tonix. Did you check your couch cushions? Collect all debts owed? Sell some of your losers? Tonmya is a winner 🏆 if just 1% of the world has fibromyalgia, that means 80 million… and it may be higher than that. My main concern is that we stay too cheap, someone in BP realizes the discrepancy and buys in. Heck even $AXSM could afford Tonix now… but if it was mostly or entirely equity deal, I would hold long given they have their own FM launch coming along with a strong CNS portfolio. Combined they would be incredible 🧐 But I would miss Seth, especially just as Tonmya is ramping up. It is really cool to see an older doctor take an idea from clinic to widespread commercial availability because he could. God Bless America 🇺🇸 end this senseless war 🙏
0 · Reply
ContinentalExpat
ContinentalExpat Mar. 15 at 10:09 PM
$CYDY Back in 2019 I followed $AXSM, wrote calls. January 2019 the price was under $3. By Feb almost $10, Apr over $13, May $23, Nov $37, early Dec $43, late Dec $103. All on positive Ph2 and 3 clinical trials for different indications. In just one year from $2.65 to $103. Could we make a case for CytoDyn in a similar way? Cancer in April or May. HIV Nov or Dec. Althzheimers and Brain Cancer somewhere in between. $0.26 to Three Fingers by December!
5 · Reply
Morgan96
Morgan96 Mar. 15 at 6:08 PM
Interested in getting thoughts in an effort to see all perspectives of $AXSM. Various thoughts should go into any investment imo. First for bears, what are the things you see that are going well for the company? Second for bulls, what are the things you see that are concerning for the company?
2 · Reply
Vakeshka
Vakeshka Mar. 15 at 7:32 AM
$AXSM I second that. When the company gets to MC of or is BO for $30B, all longs will need to get together to celebrate, I'll be happ buying Mike drinks all day long and twice in Sunday!
2 · Reply
ChicoP
ChicoP Mar. 14 at 1:33 AM
$AXSM Any true long should thank Mike826 for years of intelligent analysis of Axsome and the stock price. With all the garbage posted on these sites. This person is why I come back here.
4 · Reply
donnkeyotee
donnkeyotee Mar. 13 at 7:32 PM
$AXSM $AXSM saw this on X. Any thoughts from people more knowledgeable than me. This name typically doesnt see too much options activity. Timing is right after pdufa date so could be a a hedge or possibly insight into the ssNDA submission
1 · Reply
bemore
bemore Mar. 13 at 5:11 PM
$AXSM RBC Capital analyst Leonid Timashev maintained a Buy rating on Axsome Therapeutics today and set a price target of $222.00.ACCORDING to TipRanks, Timashev is a 5-star analyst with an average return of 13.7% and a 49.80% success rate. Timashev covers the Healthcare sector, focusing on stocks such as Cytokinetics, Exelixis, and Axsome Therapeutics. The word on The Street in general, suggests a Strong Buy analyst consensus rating for Axsome Therapeutics with a $221.87 average price target. RBD says 85% chance of approval of axs05 and a 30% increase in stock price.
0 · Reply