Market Cap 60.16M
Revenue (ttm) 43.77M
Net Income (ttm) -35.04M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -80.05%
Debt to Equity Ratio 0.00
Volume 16,400
Avg Vol 46,522
Day's Range N/A - N/A
Shares Out 6.58M
Stochastic %K 47%
Beta -0.14
Analysts Sell
Price Target $20.00

Company Profile

Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of masked immuno-oncology therapies. The company's pipeline includes XTX501, a bispecific PD-1 / masked IL-2, for patients with metastatic non-small cell lung cancer; Efarindodekin alfa, an investigational, masked IL-12, that is in Phase 2 clinical trial for patients with advanced solid tumors; and Vilastobart, an investigational tumor-activated, Fc-enhanced, high affinity binding anti-CTLA...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 524 2466
Website: xiliotx.com
Address:
828 Winter Street, Suite 300, Waltham, United States
809trader
809trader Jul. 4 at 11:48 AM
$XLO out of the 6+ million shares outstanding only 3.8 millions are available to trade. Out of that 3.8 millions only 1.4 million shares are held by retail investor. Think about that. 1.3 million shares. Any partnership announcement or good milestone payment will send this piggy flying. Now I see why they didn’t PR AbbVie $6 million milestone payment. They knew they can’t hold the stock down. My senses are saying we are getting a PR very soon. HAPPY 250th BIRTHDAY AMERICA !!! ❤️🇺🇸
0 · Reply
biohuntress
biohuntress Jun. 30 at 6:50 PM
$XLO I've become wary of the CEO's enthusiasm but she mentioned XLO wanted to carve out a clause that reserves the right to pair Vilastobart with XLO drugs.....that sounds like they were in partnership discussions pending the just completed Vilastobart trial....it's strange how Vilastobart has gone off the radar....partnership would be a nice surprise
2 · Reply
LabPsycho
LabPsycho Jun. 30 at 6:03 PM
$XLO 1. Low float + 2. Trading at a fraction of cash! 3. Trading at an even smaller fraction of potentially more cash from partners later this year 4. Gilead, Abbvie, Roche partners
0 · Reply
LabPsycho
LabPsycho Jun. 30 at 5:58 PM
$XLO Updated presentation out yesterday https://ir.xiliotx.com/static-files/0858e9cf-fd93-4938-8f02-396e622e8edf
1 · Reply
LabPsycho
LabPsycho Jun. 30 at 2:54 PM
$XLO Look at the newcomers / posters below...looks like part of the PrePump gang moving in to help run this up to $19 or so soon?
2 · Reply
FutureScout
FutureScout Jun. 30 at 1:31 PM
$XLO is currently priced at $9.27.THE core narrative for the company involves the progress of its masked platform technology. With a planned IND submission for XTX501 in mid-2026 and Phase 1 initiation later this year, the company is preparing for significant clinical catalysts.The presence of major pharmaceutical shareholders continues to provide a foundation for market interest.
1 · Reply
AlphaVisionn
AlphaVisionn Jun. 30 at 1:30 PM
$XLO is currently trading at $9.27.THE company is advancing its clinical pipeline, with plans for an IND submission in mid-2026.Focus remains on the development of XTX501, a bispecific PD-1 and masked IL-2 candidate. Market interest is supported by a stable shareholder base involving major pharmaceutical partners.
0 · Reply
809trader
809trader Jun. 30 at 12:50 PM
$XLO have a least 2 milestone that were supposed happen in the first half/second quarter. Today is the last day.
0 · Reply
TopSarge
TopSarge Jun. 29 at 6:12 PM
$XLO This one has momentum potential
1 · Reply
Jtlo
Jtlo Jun. 29 at 4:38 PM
$XLO come on 20
0 · Reply
Latest News on XLO
Xilio Therapeutics Registration statement: Registration filing

May 27, 2026, 8:00 AM EDT - 5 weeks ago

Xilio Therapeutics Registration statement: Registration filing


Xilio Therapeutics files $250M mixed securities shelf

2026-05-12T16:42:54.000Z - 7 weeks ago

Xilio Therapeutics files $250M mixed securities shelf


Xilio Therapeutics Registration statement: Registration filing

May 12, 2026, 8:00 AM EDT - 7 weeks ago

Xilio Therapeutics Registration statement: Registration filing


Xilio Therapeutics Earnings release: Q1 2026

May 12, 2026, 7:30 AM EDT - 7 weeks ago

Xilio Therapeutics Earnings release: Q1 2026


Xilio Therapeutics Quarterly report: Q1 2026

May 12, 2026, 7:30 AM EDT - 7 weeks ago

Xilio Therapeutics Quarterly report: Q1 2026


Xilio Therapeutics Proxy statement: Proxy filing

Apr 28, 2026, 8:00 AM EDT - 2 months ago

Xilio Therapeutics Proxy statement: Proxy filing


Xilio announces new preclinical data for XTX601 at AACR

2026-04-17T20:20:14.000Z - 2 months ago

Xilio announces new preclinical data for XTX601 at AACR


Xilio Therapeutics appoints Blanchard to its Board of Directors

2026-04-16T11:40:39.000Z - 2 months ago

Xilio Therapeutics appoints Blanchard to its Board of Directors


Xilio Therapeutics Appoints Cheryl R. Blanchard, Ph.D.

Apr 16, 2026, 7:30 AM EDT - 2 months ago

Xilio Therapeutics Appoints Cheryl R. Blanchard, Ph.D.


Xilio Therapeutics Annual report: Q4 2025

Mar 23, 2026, 7:30 AM EDT - 3 months ago

Xilio Therapeutics Annual report: Q4 2025


Xilio Therapeutics Earnings release: Q4 2025

Mar 23, 2026, 7:30 AM EDT - 3 months ago

Xilio Therapeutics Earnings release: Q4 2025


Xilio Therapeutics Annual report: Q4 2025

Mar 23, 2026, 7:30 AM EDT - 3 months ago

Xilio Therapeutics Annual report: Q4 2025


Xilio Therapeutics Inc trading halted, news pending

2026-03-13T23:52:06.000Z - 4 months ago

Xilio Therapeutics Inc trading halted, news pending


Xilio Therapeutics announces 1-for-14 reverse stock split

2026-03-12T12:45:03.000Z - 4 months ago

Xilio Therapeutics announces 1-for-14 reverse stock split


Xilio Therapeutics Announces 1-for-14 Reverse Stock Split

Mar 12, 2026, 8:30 AM EDT - 4 months ago

Xilio Therapeutics Announces 1-for-14 Reverse Stock Split


Xilio Therapeutics Announces Pricing of Underwritten Offering

Feb 11, 2026, 9:34 PM EST - 5 months ago

Xilio Therapeutics Announces Pricing of Underwritten Offering


Xilio Therapeutics Proxy statement: Proxy Filing

Jan 26, 2026, 7:00 AM EST - 5 months ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics Proxy statement: Proxy Filing

Jan 16, 2026, 7:00 AM EST - 6 months ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics Earnings release: Q3 2025

Nov 13, 2025, 4:00 PM EST - 8 months ago

Xilio Therapeutics Earnings release: Q3 2025


Xilio Therapeutics Quarterly report: Q3 2025

Nov 13, 2025, 4:00 PM EST - 8 months ago

Xilio Therapeutics Quarterly report: Q3 2025


Xilio Therapeutics reports Q3 EPS (11c) vs (22c) last year

2025-11-13T12:35:19.000Z - 8 months ago

Xilio Therapeutics reports Q3 EPS (11c) vs (22c) last year


Xilio Therapeutics Transcript: Status Update

Nov 10, 2025, 4:30 PM EST - 8 months ago

Xilio Therapeutics Transcript: Status Update


Xilio Therapeutics Press release: Status Update

Nov 10, 2025, 4:30 PM EST - 8 months ago

Xilio Therapeutics Press release: Status Update


Xilio Therapeutics Slides: Status Update

Nov 10, 2025, 4:30 PM EST - 8 months ago

Xilio Therapeutics Slides: Status Update


Xilio Therapeutics presents new data across portfolio at SITC

2025-11-07T14:21:23.000Z - 8 months ago

Xilio Therapeutics presents new data across portfolio at SITC


Xilio Therapeutics Proxy statement: Proxy Filing

Oct 20, 2025, 8:00 AM EDT - 9 months ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics Proxy statement: Proxy Filing

Oct 10, 2025, 8:00 AM EDT - 9 months ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics sees cash runway into 1Q27

2025-09-09T11:35:08.000Z - 10 months ago

Xilio Therapeutics sees cash runway into 1Q27


Xilio Therapeutics reports Q2 EPS (16c) vs (24c) last year

2025-08-14T11:35:14.000Z - 11 months ago

Xilio Therapeutics reports Q2 EPS (16c) vs (24c) last year


Xilio Therapeutics Quarterly report: Q2 2025

Aug 14, 2025, 7:30 AM EDT - 11 months ago

Xilio Therapeutics Quarterly report: Q2 2025


Xilio Therapeutics Earnings release: Q2 2025

Aug 14, 2025, 7:30 AM EDT - 11 months ago

Xilio Therapeutics Earnings release: Q2 2025


Xilio Therapeutics initiated with an Outperform at Leerink

2025-08-06T10:32:01.000Z - 11 months ago

Xilio Therapeutics initiated with an Outperform at Leerink


Xilio Therapeutics Slides: Corporate Presentation

Jun 5, 2025, 7:00 AM EDT - 1 year ago

Xilio Therapeutics Slides: Corporate Presentation


Xilio Therapeutics Proxy statement: Proxy Filing

Jun 3, 2025, 8:00 AM EDT - 1 year ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics announces pricing of $50M public offering

2025-06-02T12:55:18.000Z - 1 year ago

Xilio Therapeutics announces pricing of $50M public offering


Xilio Therapeutics Announces Proposed Public Offering

Jun 2, 2025, 6:11 AM EDT - 1 year ago

Xilio Therapeutics Announces Proposed Public Offering


Xilio Therapeutics Earnings release: Q1 2025

May 7, 2025, 6:00 PM EDT - 1 year ago

Xilio Therapeutics Earnings release: Q1 2025


Xilio Therapeutics Quarterly report: Q1 2025

May 7, 2025, 6:00 PM EDT - 1 year ago

Xilio Therapeutics Quarterly report: Q1 2025


Xilio Therapeutics Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics Proxy statement: Proxy Filing

Apr 28, 2025, 8:00 AM EDT - 1 year ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics Proxy statement: Proxy Filing

Apr 18, 2025, 8:00 AM EDT - 1 year ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics Earnings release: Q4 2024

Mar 11, 2025, 7:30 AM EDT - 1 year ago

Xilio Therapeutics Earnings release: Q4 2024


Xilio Therapeutics Annual report: Q4 2024

Mar 11, 2025, 7:30 AM EDT - 1 year ago

Xilio Therapeutics Annual report: Q4 2024


Xilio Therapeutics Transcript: Study Update

Feb 12, 2025, 8:30 AM EST - 1 year ago

Xilio Therapeutics Transcript: Study Update


Xilio Therapeutics Press release: Study Update

Feb 12, 2025, 8:30 AM EST - 1 year ago

Xilio Therapeutics Press release: Study Update


Xilio Therapeutics Slides: Study Update

Feb 12, 2025, 8:30 AM EST - 1 year ago

Xilio Therapeutics Slides: Study Update


Xilio Therapeutics Transcript: Study Update

Jan 22, 2025, 8:30 AM EST - 1 year ago

Xilio Therapeutics Transcript: Study Update


Xilio Therapeutics Press release: Study Update

Jan 22, 2025, 8:30 AM EST - 1 year ago

Xilio Therapeutics Press release: Study Update


Xilio Therapeutics Transcript: Study Update

Nov 7, 2024, 4:30 PM EST - 1 year ago

Xilio Therapeutics Transcript: Study Update


Xilio Therapeutics Press release: Study Update

Nov 7, 2024, 4:30 PM EST - 1 year ago

Xilio Therapeutics Press release: Study Update


Xilio Therapeutics Slides: Study Update

Nov 7, 2024, 4:30 PM EST - 1 year ago

Xilio Therapeutics Slides: Study Update


Xilio Therapeutics Quarterly report: Q3 2024

Nov 7, 2024, 9:00 AM EST - 1 year ago

Xilio Therapeutics Quarterly report: Q3 2024


Xilio Therapeutics Earnings release: Q3 2024

Nov 7, 2024, 9:00 AM EST - 1 year ago

Xilio Therapeutics Earnings release: Q3 2024


Xilio Therapeutics Quarterly report: Q2 2024

Aug 8, 2024, 7:30 AM EDT - 2 years ago

Xilio Therapeutics Quarterly report: Q2 2024


Xilio Therapeutics Earnings release: Q2 2024

Aug 8, 2024, 7:30 AM EDT - 2 years ago

Xilio Therapeutics Earnings release: Q2 2024


Xilio Therapeutics Quarterly report: Q1 2024

May 14, 2024, 7:00 AM EDT - 2 years ago

Xilio Therapeutics Quarterly report: Q1 2024


Xilio Therapeutics Earnings release: Q1 2024

May 14, 2024, 7:00 AM EDT - 2 years ago

Xilio Therapeutics Earnings release: Q1 2024


Xilio Therapeutics Registration statement: Registration Filing

Apr 30, 2024, 8:00 AM EDT - 2 years ago

Xilio Therapeutics Registration statement: Registration Filing


Xilio Therapeutics Proxy statement: Proxy Filing

Apr 25, 2024, 8:00 AM EDT - 2 years ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics Proxy statement: Proxy Filing

Apr 25, 2024, 8:00 AM EDT - 2 years ago

Xilio Therapeutics Proxy statement: Proxy Filing


Xilio Therapeutics Annual report: Q4 2023

Apr 1, 2024, 4:00 PM EDT - 2 years ago

Xilio Therapeutics Annual report: Q4 2023


Xilio Therapeutics Earnings release: Q4 2023

Apr 1, 2024, 4:00 PM EDT - 2 years ago

Xilio Therapeutics Earnings release: Q4 2023


Xilio Therapeutics Slides: Corporate Presentation

Jan 8, 2024, 7:00 AM EST - 2 years ago

Xilio Therapeutics Slides: Corporate Presentation


809trader
809trader Jul. 4 at 11:48 AM
$XLO out of the 6+ million shares outstanding only 3.8 millions are available to trade. Out of that 3.8 millions only 1.4 million shares are held by retail investor. Think about that. 1.3 million shares. Any partnership announcement or good milestone payment will send this piggy flying. Now I see why they didn’t PR AbbVie $6 million milestone payment. They knew they can’t hold the stock down. My senses are saying we are getting a PR very soon. HAPPY 250th BIRTHDAY AMERICA !!! ❤️🇺🇸
0 · Reply
biohuntress
biohuntress Jun. 30 at 6:50 PM
$XLO I've become wary of the CEO's enthusiasm but she mentioned XLO wanted to carve out a clause that reserves the right to pair Vilastobart with XLO drugs.....that sounds like they were in partnership discussions pending the just completed Vilastobart trial....it's strange how Vilastobart has gone off the radar....partnership would be a nice surprise
2 · Reply
LabPsycho
LabPsycho Jun. 30 at 6:03 PM
$XLO 1. Low float + 2. Trading at a fraction of cash! 3. Trading at an even smaller fraction of potentially more cash from partners later this year 4. Gilead, Abbvie, Roche partners
0 · Reply
LabPsycho
LabPsycho Jun. 30 at 5:58 PM
$XLO Updated presentation out yesterday https://ir.xiliotx.com/static-files/0858e9cf-fd93-4938-8f02-396e622e8edf
1 · Reply
LabPsycho
LabPsycho Jun. 30 at 2:54 PM
$XLO Look at the newcomers / posters below...looks like part of the PrePump gang moving in to help run this up to $19 or so soon?
2 · Reply
FutureScout
FutureScout Jun. 30 at 1:31 PM
$XLO is currently priced at $9.27.THE core narrative for the company involves the progress of its masked platform technology. With a planned IND submission for XTX501 in mid-2026 and Phase 1 initiation later this year, the company is preparing for significant clinical catalysts.The presence of major pharmaceutical shareholders continues to provide a foundation for market interest.
1 · Reply
AlphaVisionn
AlphaVisionn Jun. 30 at 1:30 PM
$XLO is currently trading at $9.27.THE company is advancing its clinical pipeline, with plans for an IND submission in mid-2026.Focus remains on the development of XTX501, a bispecific PD-1 and masked IL-2 candidate. Market interest is supported by a stable shareholder base involving major pharmaceutical partners.
0 · Reply
809trader
809trader Jun. 30 at 12:50 PM
$XLO have a least 2 milestone that were supposed happen in the first half/second quarter. Today is the last day.
0 · Reply
TopSarge
TopSarge Jun. 29 at 6:12 PM
$XLO This one has momentum potential
1 · Reply
Jtlo
Jtlo Jun. 29 at 4:38 PM
$XLO come on 20
0 · Reply
LabPsycho
LabPsycho Jun. 29 at 3:40 PM
$XLO @809trader Quite possibly, (without your help this time?) the $XLO melt up to $16 has begun?
1 · Reply
809trader
809trader Jun. 29 at 3:33 PM
$XLO 🤫🤫🤫🤫🤫🤫😎😎😎😎
0 · Reply
focafoca99
focafoca99 Jun. 29 at 11:44 AM
$XLO designated Ben Harshbarger as chief legal officer.
0 · Reply
biohuntress
biohuntress Jun. 26 at 10:35 PM
$XLO "Xilio is deploying its clinically validated masking technology to advance several highly differentiated bi- and multispecific molecules towards clinical development XTX501, Xilio’s PD1/masked IL-2 bispecific has the potential to be a foundational backbone therapy for combination regimens across a broad range of solid tumors, and the program is on track to advance into the clinic this year XTX601, Xilio’s masked CLDN18.2 T-cell engager and Xilio’s masked PSMA+STEAP1 dual-TAA targeted T-cell engager with co-stimulation both have first-in- class potential and further demonstrate the power of our masking technology to unlock the potential of T-cell engagers"
0 · Reply
AskSmacker
AskSmacker Jun. 26 at 5:37 PM
$XLO competitors are showing promise, systemic tolerability remains an issue, and XTX501 is designed to address it
0 · Reply
biohuntress
biohuntress Jun. 25 at 7:44 PM
$XLO Vilastobart trial completed 6/16/26......are we gonna get a partner?...XTX 501 IND "mid 26"....hope we are basing here waiting for some news https://tinyurl.com/yfv7f9kj
3 · Reply
LabPsycho
LabPsycho Jun. 23 at 1:59 PM
$XLO @809trader Now that's what I see as someone stepping up to the plate! The real game starts for me at $12.4 and above. Good luck
1 · Reply
AskSmacker
AskSmacker Jun. 23 at 12:44 AM
$XLO "FDA Actions to Accelerate and Modernize Early and Late-Stage Clinical Development" Should bode well for the upcomingIND submission. https://www.fda.gov/industry/fda-actions-accelerate-and-modernize-early-and-late-stage-clinical-development
1 · Reply
809trader
809trader Jun. 22 at 9:00 PM
$XLO I’m done with this games. Watch tomorrow!!!
1 · Reply
LabPsycho
LabPsycho Jun. 22 at 2:28 PM
$XLO IMO, Based on today's paltry (again) volume it looks like if this thing ever trades 1 million or more shares in a day, it would go to either 3 or 22 on said hypothetical high volume trading day.
0 · Reply
LabPsycho
LabPsycho Jun. 22 at 1:47 PM
$XLO @809trader Even a rounding error on that deal used towards XLO could 5X it.
0 · Reply
809trader
809trader Jun. 19 at 3:17 PM
$XLO can you please buy this puppy next: https://x.com/mroliverbarnes/status/2067976305631481867?s=46&t=wHopsM6AxwgEZIfi0ZU3Hg
0 · Reply