Market Cap 700.79M
Revenue (ttm) 64.38M
Net Income (ttm) -56.42M
EPS (ttm) N/A
PE Ratio 29.43
Forward PE 28.42
Profit Margin -87.64%
Debt to Equity Ratio 0.00
Volume 1,486,900
Avg Vol 630,524
Day's Range N/A - N/A
Shares Out 50.67M
Stochastic %K 93%
Beta 0.17
Analysts Sell
Price Target $15.83

Company Profile

Theravance Biopharma, Inc., a biopharmaceutical company, develops and commercializes medicines in the United States. It offers YUPELRI, a once-daily, nebulized long-acting muscarinic antagonist for the treatment of chronic obstructive pulmonary disease (COPD). Its late-stage investigational once-daily norepinephrine reuptake inhibitor, Ampreloxetine is in the development for symptomatic neurogenic orthostatic hypotension (nOH) in patients with Multiple System Atrophy (MSA). It has a strategic co...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 808 6000
Address:
901 Gateway Boulevard, South San Francisco, United States
Itinerant
Itinerant Mar. 12 at 4:52 PM
$TBPH I am bullish on today's earnings report, odd as that might seem. My logic is this. The key is the operational restructuring after the failed trial, their only trial. If one applies the operational plan to the actual operating numbers, and recognizes the costs of restructuring, then the fair value of the company is about $21 on a continuing basis (+50%). In addition, the Board committee for shareholder value has been recharged into prompt action. Translation: let's sell the company. Doing the math, I see a sale value of about $27 per share (+100%). Selling the company should not be difficult because the balance sheet is strong, and the time horizon on the COPD product remains durable. I believe this will be made clear in the earnings report. I too am awaiting some detailed numbers from the ER. However, the analysts have said little to nothing so far. Once they run the numbers after the ER, they will revise their outlook, and be pumping the sale value. JMO
0 · Reply
Estimize
Estimize Mar. 11 at 12:00 PM
Wall St is expecting -0.06 EPS for $TBPH Q1 [Reporting 05/13 AMC] http://www.estimize.com/intro/tbph?chart=historical&metric_name=eps&utm_c
1 · Reply
Delgado_Suri22
Delgado_Suri22 Mar. 5 at 5:39 PM
$TBPH biotech range compression building watching for catalyst driven volume
0 · Reply
Itinerant
Itinerant Mar. 4 at 7:04 PM
$TBPH The company blew the trial. Ok, that costs $250 million in market cap. That happened in a nano second. However, the company has since announced a major overhead cut, and step up of strategic alternative consideration: i.e. sell the company. Yet, the market does not appear to have reacted to that news. The market cap is now under valued substantially on this news. I bought. JMO
1 · Reply
ZacksResearch
ZacksResearch Mar. 4 at 4:21 PM
$TBPH just got crushed — down 26% after a major clinical setback ⚠️ Theravance Biopharma’s phase III CYPRESS study of ampreloxetine missed key endpoints, and management is halting the program altogether. Late-stage failure + program shutdown is a brutal combo for sentiment. If you’re holding or watching, you’ll want the full breakdown. 👉 https://www.zacks.com/stock/news/2878770/tbph-stock-plunges-26-on-failure-of-late-stage-msa-study?cid=sm-stocktwits-2-2878770-teaser-35944&ADID=SYND_STOCKTWITS_TWEET_2_2878770_TEASER_35944
0 · Reply
ZacksResearch
ZacksResearch Mar. 4 at 3:21 PM
$TBPH plunges 26% after CYPRESS study failure! 🚨 The late-stage trial for ampreloxetine missed its primary endpoint, leading TBPH to wind down the program and consider strategic options, including a potential sale. Despite the setback, TBPH's shares have gained 43.6% over the past year. Full breakdown here 👉 https://www.zacks.com/stock/news/2878770/tbph-stock-plunges-26-on-failure-of-late-stage-msa-study?cid=sm-stocktwits-2-2878770-body-35943&ADID=SYND_STOCKTWITS_TWEET_2_2878770_BODY_35943
0 · Reply
OGTDeepWaters
OGTDeepWaters Mar. 4 at 1:57 AM
$TBPH Next time someone says hey invest in this biotech, think about the numbers first, and yes your welcome, perspective in investing is important.
0 · Reply
Tradebub
Tradebub Mar. 3 at 7:58 PM
$TBPH Much more downside. This company is a failure (with some cash).
0 · Reply
anachartanalyst
anachartanalyst Mar. 3 at 5:02 PM
$TBPH https://anachart.com/wp-content/uploads/ana_temp/1772557324_soc-img.jpg
0 · Reply
topstockalerts
topstockalerts Mar. 3 at 4:51 PM
Theravance Biopharma shares fell after the company announced that its Phase 3 CYPRESS trial of ampreloxetine for symptomatic neurogenic orthostatic hypotension in patients with multiple system atrophy failed to meet its primary endpoint. The study did not achieve statistical significance in the change of the Orthostatic Hypotension Symptom Assessment composite score at Week 8 during the randomized withdrawal period, with similar trends seen in secondary endpoints. As a result, the company will discontinue the ampreloxetine program. Following the setback, Theravance’s Strategic Review Committee is accelerating its evaluation of options to maximize shareholder value, including a potential sale of the company, working with financial advisor Lazard. The company also announced a major restructuring aimed at reducing its cost base by about 60% (approximately $70 million), including cutting roughly 50% of its workforce, shutting down R&D, and significantly reducing G&A expenses. $TBPH
0 · Reply
Latest News on TBPH
Theravance Biopharma Plummets As Phase 3 Study Falls Short

Mar 3, 2026, 1:19 PM EST - 18 days ago

Theravance Biopharma Plummets As Phase 3 Study Falls Short


Theravance Biopharma, Inc. (TBPH) Q1 2025 Earnings Call Transcript

May 10, 2025, 4:35 PM EDT - 11 months ago

Theravance Biopharma, Inc. (TBPH) Q1 2025 Earnings Call Transcript


Itinerant
Itinerant Mar. 12 at 4:52 PM
$TBPH I am bullish on today's earnings report, odd as that might seem. My logic is this. The key is the operational restructuring after the failed trial, their only trial. If one applies the operational plan to the actual operating numbers, and recognizes the costs of restructuring, then the fair value of the company is about $21 on a continuing basis (+50%). In addition, the Board committee for shareholder value has been recharged into prompt action. Translation: let's sell the company. Doing the math, I see a sale value of about $27 per share (+100%). Selling the company should not be difficult because the balance sheet is strong, and the time horizon on the COPD product remains durable. I believe this will be made clear in the earnings report. I too am awaiting some detailed numbers from the ER. However, the analysts have said little to nothing so far. Once they run the numbers after the ER, they will revise their outlook, and be pumping the sale value. JMO
0 · Reply
Estimize
Estimize Mar. 11 at 12:00 PM
Wall St is expecting -0.06 EPS for $TBPH Q1 [Reporting 05/13 AMC] http://www.estimize.com/intro/tbph?chart=historical&metric_name=eps&utm_c
1 · Reply
Delgado_Suri22
Delgado_Suri22 Mar. 5 at 5:39 PM
$TBPH biotech range compression building watching for catalyst driven volume
0 · Reply
Itinerant
Itinerant Mar. 4 at 7:04 PM
$TBPH The company blew the trial. Ok, that costs $250 million in market cap. That happened in a nano second. However, the company has since announced a major overhead cut, and step up of strategic alternative consideration: i.e. sell the company. Yet, the market does not appear to have reacted to that news. The market cap is now under valued substantially on this news. I bought. JMO
1 · Reply
ZacksResearch
ZacksResearch Mar. 4 at 4:21 PM
$TBPH just got crushed — down 26% after a major clinical setback ⚠️ Theravance Biopharma’s phase III CYPRESS study of ampreloxetine missed key endpoints, and management is halting the program altogether. Late-stage failure + program shutdown is a brutal combo for sentiment. If you’re holding or watching, you’ll want the full breakdown. 👉 https://www.zacks.com/stock/news/2878770/tbph-stock-plunges-26-on-failure-of-late-stage-msa-study?cid=sm-stocktwits-2-2878770-teaser-35944&ADID=SYND_STOCKTWITS_TWEET_2_2878770_TEASER_35944
0 · Reply
ZacksResearch
ZacksResearch Mar. 4 at 3:21 PM
$TBPH plunges 26% after CYPRESS study failure! 🚨 The late-stage trial for ampreloxetine missed its primary endpoint, leading TBPH to wind down the program and consider strategic options, including a potential sale. Despite the setback, TBPH's shares have gained 43.6% over the past year. Full breakdown here 👉 https://www.zacks.com/stock/news/2878770/tbph-stock-plunges-26-on-failure-of-late-stage-msa-study?cid=sm-stocktwits-2-2878770-body-35943&ADID=SYND_STOCKTWITS_TWEET_2_2878770_BODY_35943
0 · Reply
OGTDeepWaters
OGTDeepWaters Mar. 4 at 1:57 AM
$TBPH Next time someone says hey invest in this biotech, think about the numbers first, and yes your welcome, perspective in investing is important.
0 · Reply
Tradebub
Tradebub Mar. 3 at 7:58 PM
$TBPH Much more downside. This company is a failure (with some cash).
0 · Reply
anachartanalyst
anachartanalyst Mar. 3 at 5:02 PM
$TBPH https://anachart.com/wp-content/uploads/ana_temp/1772557324_soc-img.jpg
0 · Reply
topstockalerts
topstockalerts Mar. 3 at 4:51 PM
Theravance Biopharma shares fell after the company announced that its Phase 3 CYPRESS trial of ampreloxetine for symptomatic neurogenic orthostatic hypotension in patients with multiple system atrophy failed to meet its primary endpoint. The study did not achieve statistical significance in the change of the Orthostatic Hypotension Symptom Assessment composite score at Week 8 during the randomized withdrawal period, with similar trends seen in secondary endpoints. As a result, the company will discontinue the ampreloxetine program. Following the setback, Theravance’s Strategic Review Committee is accelerating its evaluation of options to maximize shareholder value, including a potential sale of the company, working with financial advisor Lazard. The company also announced a major restructuring aimed at reducing its cost base by about 60% (approximately $70 million), including cutting roughly 50% of its workforce, shutting down R&D, and significantly reducing G&A expenses. $TBPH
0 · Reply
stockanalysis_
stockanalysis_ Mar. 3 at 4:45 PM
Losers Today: $ITRM $ELPW $MAIA $TBPH $WORX Save this screener: https://stockanalysis.com/markets/losers/?ref=saveontrading
0 · Reply
Tradebub
Tradebub Mar. 3 at 4:18 PM
$TBPH Notice the analyst upgrade just before bad news.
0 · Reply
mikesterz7
mikesterz7 Mar. 3 at 4:12 PM
$TBPH The company reported that its Phase 3 CYPRESS study of ampreloxetine in patients with hypotension failed to meet its primary endpoint.
0 · Reply
StocktwitsNews
StocktwitsNews Mar. 3 at 3:38 PM
TBPH Stock Slumps 30%, Falls Below 200-DMA For First Time In Over 9 Months As Phase 3 Study Misses Primary Endpoint $TBPH $JSML $XPH $IHE $IWC https://stocktwits.com/news/equity/markets/tbph-stock-slumps-theravance-misses-primary-endpoint-phase-3-study/cZdeSXwRIPL
0 · Reply
Tradebub
Tradebub Mar. 3 at 3:10 PM
$TBPH No brainer short. Going in big.
0 · Reply
Messerschmittbf109
Messerschmittbf109 Mar. 3 at 2:54 PM
$TBPH 12 value is 500M
0 · Reply
Itinerant
Itinerant Mar. 3 at 2:50 PM
$TBPH The loss of market cap on this failed P3 is spot on the benchmark value of a P3: $250 million. Stock is correctly valued.
0 · Reply
Tradebub
Tradebub Mar. 3 at 2:14 PM
$TBPH News is not known yet. SHORT IT right now.
1 · Reply
notreload_ai
notreload_ai Mar. 3 at 1:56 PM
$TBPH ampreloxetine failed its Phase 3 CYPRESS study for nOH in MSA. Company winds down program, cuts costs ~60%, focuses on YUPELRi cash flow, and speeds up strategic alternatives review to maximize shareholder value. https://notreload.xyz/theravance-biopharma-phase-3-failure-triggers-cost-cuts-and-sale-exploration/
0 · Reply
OpenOutcrier
OpenOutcrier Mar. 3 at 1:56 PM
$TBPH (-28.1% pre) Theravance Biopharma Reports Phase 3 CYPRESS Study Did Not Meet Primary Endpoint; Board Accelerates Strategic Review and Announces Cost Reduction Actions https://ooc.bz/l/95298
0 · Reply
stockanalysis_
stockanalysis_ Mar. 3 at 1:56 PM
Premarket Losers: $ITRM $TBPH $MDB $MAIA $INEO Save this screener: https://stockanalysis.com/markets/premarket/losers/?ref=saveontrading
0 · Reply
Tradebub
Tradebub Mar. 3 at 1:54 PM
$TBPH Sell now. Ask questions later.
0 · Reply