Market Cap 574.97M
Revenue (ttm) 4.63M
Net Income (ttm) -201.14M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin -4,344.28%
Debt to Equity Ratio 0.00
Volume 1,270,200
Avg Vol 3,300,282
Day's Range N/A - N/A
Shares Out 181.38M
Stochastic %K 35%
Beta 2.31
Analysts Strong Sell
Price Target $7.03

Company Profile

Prime Medicine, Inc., a biotechnology company, engages in delivering genetic medicines to address the spectrum of diseases by deploying gene editing technology in the United States. Its lead therapeutic product candidate is PM359 for Chronic Granulomatous Disease, which is in Phase 1/2 clinical trial; PM577 for Wilson Disease, that is in preclinical studies; and PM647 to treat genetic disorder caused by mutations in the SERPINA1 gene, resulting in production of misfolded Z-AAT protein that accum...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 465 0013
Address:
60 First Street, Cambridge, United States
USAEquityResearch
USAEquityResearch Aug. 18 at 10:32 PM
$PRME 📊 USAEquityResearch ▼ 3.05 (-3.79%) Trend: Bearish 📉 RSI (14): 50.8 — neutral territory MACD: bullish, above signal line and rising Volume: below average 📌 Key Levels Resistance: 3.26 Support: 2.81 20-MA: 3.05 | 50-MA: 3.26 Educational content only. Not financial advice.
0 · Reply
notreload_ai
notreload_ai Aug. 18 at 9:00 PM
BMO initiates $PRME at Outperform/$9, citing its unique prime-editing tech that delivers precise DNA fixes without double-strand breaks. https://notreload.xyz/xy/bmo-outperform-on-prme-for-differentiated-gene-editing/
1 · Reply
Toro_of_Ga
Toro_of_Ga Aug. 17 at 3:16 PM
$PRME lets go..
0 · Reply
Patrick0423
Patrick0423 Aug. 17 at 12:32 PM
$PRME How’s this? I heard someone recommend him at a high-end dinner.
1 · Reply
veryboredXYZ
veryboredXYZ Aug. 15 at 12:39 AM
$PRME buying zone, stay like that til Monday pls
0 · Reply
DOGBIRD
DOGBIRD Aug. 14 at 6:11 PM
$PRME Surprise us with a deal. Solve the cash concerns. It'll pop like a slingshot.
0 · Reply
AcceleratorModel
AcceleratorModel Aug. 14 at 4:28 PM
$PRME time cmon !
0 · Reply
PorkchopSquats
PorkchopSquats Aug. 14 at 2:22 PM
0 · Reply
BIOTECH_GURU
BIOTECH_GURU Aug. 14 at 11:01 AM
$PRME They own patent for genetic editing technology that is proven on the benchtop and now has human data to support it. Best case scenario, adoption of multiple genetic conditions to include common diseases like hyperlipidemia with pcsk9 gene deletion, with no live failure signal. This would move from a rare disease TAM to a cardiovascular disease prevention/treatment TAM. This would become instantly $20B acquisition target. Worst case scenario: they get bought out for a cheap price prior to recognition of potention just like $VERV Timwline 12-24 months. Nfa. Gltya.
0 · Reply
DOGBIRD
DOGBIRD Aug. 13 at 4:39 PM
$PRME Curious if Optiprime will open more doors for deals near term.
0 · Reply
Latest News on PRME
BMO starts Prime Medicine at Outperform into 2027 readouts

2026-08-18T20:35:46.000Z - 16 hours ago

BMO starts Prime Medicine at Outperform into 2027 readouts


Prime Medicine initiated with an Outperform at BMO Capital

2026-08-18T20:25:25.000Z - 16 hours ago

Prime Medicine initiated with an Outperform at BMO Capital


Prime Medicine reports Q4 EPS (24c), consensus (26c)

2026-08-06T13:22:11.000Z - 12 days ago

Prime Medicine reports Q4 EPS (24c), consensus (26c)


Prime Medicine Quarterly report: Q2 2026

Aug 6, 2026, 7:00 AM EDT - 13 days ago

Prime Medicine Quarterly report: Q2 2026


Prime Medicine Earnings release: Q2 2026

Aug 6, 2026, 7:00 AM EDT - 13 days ago

Prime Medicine Earnings release: Q2 2026


Prime Medicine Slides: Corporate presentation

Jul 7, 2026, 7:00 AM EDT - 6 weeks ago

Prime Medicine Slides: Corporate presentation


Prime Medicine granted RMAT designation for PM359

2026-06-22T12:20:45.000Z - 2 months ago

Prime Medicine granted RMAT designation for PM359


Prime Medicine Transcript: AGM 2026

Jun 5, 2026, 2:00 PM EDT - 2 months ago

Prime Medicine Transcript: AGM 2026


Prime Medicine Slides: Corporate presentation

Jun 3, 2026, 7:00 AM EDT - 2 months ago

Prime Medicine Slides: Corporate presentation


Prime Medicine reports Q1 EPS (28c), consensus (25c)

2026-05-07T19:46:03.000Z - 3 months ago

Prime Medicine reports Q1 EPS (28c), consensus (25c)


Prime Medicine Quarterly report: Q1 2026

May 7, 2026, 7:00 AM EDT - 3 months ago

Prime Medicine Quarterly report: Q1 2026


Prime Medicine Earnings release: Q1 2026

May 7, 2026, 7:00 AM EDT - 3 months ago

Prime Medicine Earnings release: Q1 2026


Prime Medicine management to meet with Oppenheimer

2026-05-07T02:02:00.000Z - 3 months ago

Prime Medicine management to meet with Oppenheimer


Prime Medicine Proxy statement: Proxy filing

Apr 23, 2026, 8:00 AM EDT - 4 months ago

Prime Medicine Proxy statement: Proxy filing


Prime Medicine Proxy statement: Proxy filing

Apr 23, 2026, 8:00 AM EDT - 4 months ago

Prime Medicine Proxy statement: Proxy filing


Prime Medicine appoints Makhni as Chief Financial Officer

2026-04-16T12:25:29.000Z - 4 months ago

Prime Medicine appoints Makhni as Chief Financial Officer


Prime Medicine initiated with an Outperform at Oppenheimer

2026-03-12T10:26:58.000Z - 5 months ago

Prime Medicine initiated with an Outperform at Oppenheimer


Prime Medicine reports FY25 EPS ($1.35) vs ($1.65) last year

2026-03-03T13:07:13.000Z - 6 months ago

Prime Medicine reports FY25 EPS ($1.35) vs ($1.65) last year


Prime Medicine Annual report: Q4 2025

Mar 3, 2026, 8:00 AM EST - 6 months ago

Prime Medicine Annual report: Q4 2025


Prime Medicine Earnings release: Q4 2025

Mar 3, 2026, 8:00 AM EST - 6 months ago

Prime Medicine Earnings release: Q4 2025


Prime Medicine Slides: Corporate presentation

Mar 2, 2026, 7:00 AM EST - 6 months ago

Prime Medicine Slides: Corporate presentation


Prime Medicine to Participate in Upcoming Investor Conferences

Feb 25, 2026, 8:00 AM EST - 6 months ago

Prime Medicine to Participate in Upcoming Investor Conferences


Prime Medicine initiated with an Outperform at LifeSci Capital

2025-12-23T13:50:25.000Z - 8 months ago

Prime Medicine initiated with an Outperform at LifeSci Capital


Prime Medicine announces NEJM publication of PM359 data

2025-12-07T18:30:05.000Z - 9 months ago

Prime Medicine announces NEJM publication of PM359 data


Prime Medicine Transcript: KOL Event

Nov 12, 2025, 8:00 AM EST - 9 months ago

Prime Medicine Transcript: KOL Event


Prime Medicine Press release: KOL Event

Nov 12, 2025, 8:00 AM EST - 9 months ago

Prime Medicine Press release: KOL Event


Prime Medicine Slides: KOL Event

Nov 12, 2025, 8:00 AM EST - 9 months ago

Prime Medicine Slides: KOL Event


Prime Medicine Quarterly report: Q3 2025

Nov 7, 2025, 7:00 AM EST - 10 months ago

Prime Medicine Quarterly report: Q3 2025


Prime Medicine Earnings release: Q3 2025

Nov 7, 2025, 7:00 AM EST - 10 months ago

Prime Medicine Earnings release: Q3 2025


Prime Medicine Slides: Corporate Presentation

Nov 6, 2025, 7:00 AM EST - 10 months ago

Prime Medicine Slides: Corporate Presentation


Prime Medicine Slides: Corporate Presentation

Sep 17, 2025, 7:00 AM EDT - 1 year ago

Prime Medicine Slides: Corporate Presentation


Prime Medicine Quarterly report: Q2 2025

Aug 7, 2025, 8:30 AM EDT - 1 year ago

Prime Medicine Quarterly report: Q2 2025


Prime Medicine Earnings release: Q2 2025

Aug 7, 2025, 8:30 AM EDT - 1 year ago

Prime Medicine Earnings release: Q2 2025


Prime Medicine Announces Pricing of Public Offering

Jul 30, 2025, 9:33 PM EDT - 1 year ago

Prime Medicine Announces Pricing of Public Offering


Prime Medicine Proxy statement: Proxy Filing

Jul 14, 2025, 8:00 AM EDT - 1 year ago

Prime Medicine Proxy statement: Proxy Filing


Prime Medicine Proxy statement: Proxy Filing

Jul 2, 2025, 8:00 AM EDT - 1 year ago

Prime Medicine Proxy statement: Proxy Filing


Prime Medicine Slides: Corporate Presentation

Jun 25, 2025, 7:00 AM EDT - 1 year ago

Prime Medicine Slides: Corporate Presentation


Prime Medicine Proxy statement: Proxy Filing

May 19, 2025, 8:00 AM EDT - 1 year ago

Prime Medicine Proxy statement: Proxy Filing


Prime Medicine Quarterly report: Q1 2025

May 8, 2025, 7:00 AM EDT - 1 year ago

Prime Medicine Quarterly report: Q1 2025


Prime Medicine Earnings release: Q1 2025

May 8, 2025, 7:00 AM EDT - 1 year ago

Prime Medicine Earnings release: Q1 2025


Prime Medicine Proxy statement: Proxy Filing

Apr 22, 2025, 8:00 AM EDT - 1 year ago

Prime Medicine Proxy statement: Proxy Filing


Prime Medicine Proxy statement: Proxy Filing

Apr 22, 2025, 8:00 AM EDT - 1 year ago

Prime Medicine Proxy statement: Proxy Filing


Prime Medicine Annual report: Q4 2024

Feb 28, 2025, 8:00 AM EST - 1 year ago

Prime Medicine Annual report: Q4 2024


Prime Medicine Earnings release: Q4 2024

Feb 28, 2025, 8:00 AM EST - 1 year ago

Prime Medicine Earnings release: Q4 2024


Prime Medicine Slides: FY 2025

Jan 14, 2025, 6:00 PM EST - 1 year ago

Prime Medicine Slides: FY 2025


Prime Medicine Registration statement: Registration Filing

Dec 13, 2024, 7:00 AM EST - 1 year ago

Prime Medicine Registration statement: Registration Filing


Prime Medicine Transcript: Stifel 2024 Healthcare Conference

Nov 18, 2024, 1:15 PM EST - 1 year ago

Prime Medicine Transcript: Stifel 2024 Healthcare Conference


Prime Medicine Quarterly report: Q3 2024

Nov 12, 2024, 9:30 AM EST - 1 year ago

Prime Medicine Quarterly report: Q3 2024


Prime Medicine Earnings release: Q3 2024

Nov 12, 2024, 9:30 AM EST - 1 year ago

Prime Medicine Earnings release: Q3 2024


Prime Medicine Unveils Strategically Focused Pipeline

Sep 30, 2024, 7:01 AM EDT - 2 years ago

Prime Medicine Unveils Strategically Focused Pipeline


Prime Medicine Quarterly report: Q2 2024

Aug 8, 2024, 8:15 AM EDT - 2 years ago

Prime Medicine Quarterly report: Q2 2024


Prime Medicine Earnings release: Q2 2024

Aug 8, 2024, 8:15 AM EDT - 2 years ago

Prime Medicine Earnings release: Q2 2024


Prime Medicine Proxy statement: Proxy Filing

May 21, 2024, 8:00 AM EDT - 2 years ago

Prime Medicine Proxy statement: Proxy Filing


Alphabet Bought Up Two Slumping Stocks

May 12, 2024, 3:00 AM EDT - 2 years ago

Alphabet Bought Up Two Slumping Stocks

GOOG GOOGL GTLB


Prime Medicine Quarterly report: Q1 2024

May 10, 2024, 7:00 AM EDT - 2 years ago

Prime Medicine Quarterly report: Q1 2024


Prime Medicine Earnings release: Q1 2024

May 10, 2024, 7:00 AM EDT - 2 years ago

Prime Medicine Earnings release: Q1 2024


Prime Medicine Proxy statement: Proxy Filing

Apr 29, 2024, 8:00 AM EDT - 2 years ago

Prime Medicine Proxy statement: Proxy Filing


Prime Medicine Proxy statement: Proxy Filing

Apr 29, 2024, 8:00 AM EDT - 2 years ago

Prime Medicine Proxy statement: Proxy Filing


Prime Medicine Proxy statement: Proxy Filing

Apr 19, 2024, 8:00 AM EDT - 2 years ago

Prime Medicine Proxy statement: Proxy Filing


Prime Medicine Earnings release: Q4 2023

Mar 1, 2024, 7:00 AM EST - 2 years ago

Prime Medicine Earnings release: Q4 2023


Prime Medicine Annual report: Q4 2023

Mar 1, 2024, 7:00 AM EST - 2 years ago

Prime Medicine Annual report: Q4 2023


Prime Medicine Announces Pricing of Upsized Public Offering

Feb 14, 2024, 11:50 PM EST - 2 years ago

Prime Medicine Announces Pricing of Upsized Public Offering


Prime Medicine Slides: FY 2024

Jan 8, 2024, 5:15 PM EST - 2 years ago

Prime Medicine Slides: FY 2024


Prime Medicine to Present at Upcoming Investor Conferences

Nov 8, 2023, 8:00 AM EST - 3 years ago

Prime Medicine to Present at Upcoming Investor Conferences


Prime Medicine Quarterly report: Q3 2023

Nov 3, 2023, 8:00 AM EDT - 3 years ago

Prime Medicine Quarterly report: Q3 2023


Prime Medicine Earnings release: Q3 2023

Nov 3, 2023, 8:00 AM EDT - 3 years ago

Prime Medicine Earnings release: Q3 2023


Prime Medicine Registration statement: Registration Filing

Nov 3, 2023, 8:00 AM EDT - 3 years ago

Prime Medicine Registration statement: Registration Filing


USAEquityResearch
USAEquityResearch Aug. 18 at 10:32 PM
$PRME 📊 USAEquityResearch ▼ 3.05 (-3.79%) Trend: Bearish 📉 RSI (14): 50.8 — neutral territory MACD: bullish, above signal line and rising Volume: below average 📌 Key Levels Resistance: 3.26 Support: 2.81 20-MA: 3.05 | 50-MA: 3.26 Educational content only. Not financial advice.
0 · Reply
notreload_ai
notreload_ai Aug. 18 at 9:00 PM
BMO initiates $PRME at Outperform/$9, citing its unique prime-editing tech that delivers precise DNA fixes without double-strand breaks. https://notreload.xyz/xy/bmo-outperform-on-prme-for-differentiated-gene-editing/
1 · Reply
Toro_of_Ga
Toro_of_Ga Aug. 17 at 3:16 PM
$PRME lets go..
0 · Reply
Patrick0423
Patrick0423 Aug. 17 at 12:32 PM
$PRME How’s this? I heard someone recommend him at a high-end dinner.
1 · Reply
veryboredXYZ
veryboredXYZ Aug. 15 at 12:39 AM
$PRME buying zone, stay like that til Monday pls
0 · Reply
DOGBIRD
DOGBIRD Aug. 14 at 6:11 PM
$PRME Surprise us with a deal. Solve the cash concerns. It'll pop like a slingshot.
0 · Reply
AcceleratorModel
AcceleratorModel Aug. 14 at 4:28 PM
$PRME time cmon !
0 · Reply
PorkchopSquats
PorkchopSquats Aug. 14 at 2:22 PM
0 · Reply
BIOTECH_GURU
BIOTECH_GURU Aug. 14 at 11:01 AM
$PRME They own patent for genetic editing technology that is proven on the benchtop and now has human data to support it. Best case scenario, adoption of multiple genetic conditions to include common diseases like hyperlipidemia with pcsk9 gene deletion, with no live failure signal. This would move from a rare disease TAM to a cardiovascular disease prevention/treatment TAM. This would become instantly $20B acquisition target. Worst case scenario: they get bought out for a cheap price prior to recognition of potention just like $VERV Timwline 12-24 months. Nfa. Gltya.
0 · Reply
DOGBIRD
DOGBIRD Aug. 13 at 4:39 PM
$PRME Curious if Optiprime will open more doors for deals near term.
0 · Reply
rweb
rweb Aug. 13 at 3:55 PM
$PRME is this thing alive?
0 · Reply
Quantumup
Quantumup Aug. 12 at 4:48 PM
Raymond James reiterated $MNPR Outperform-$123 and said -- We continue to model ALXN1840 approval and launch in 2027—Remain Outperform rated on MNPR shares following 2Q26 update. $RARE $PRME ETON Vivet Therapeutics - PFE AZN TELO Orphalan Raymond James added—All eyes remain focused on the rolling NDA submission for ALXN1840 in Wilson disease, which was recently initiated in July and the company expects to complete in the coming months. Recall, this allows FDA to receive and begin reviewing specific application sections as they are submitted, but acceptance of the application and PDUFA date assignment cannot occur until the application is complete and fully received. ALXN1840 does have Fast Track designation, which could lead to a shorter review time once the application is complete. We continue to model ALXN1840 approval and launch in 2027.
0 · Reply
ATTAB0Y
ATTAB0Y Aug. 12 at 4:44 PM
$PRME USPTO publishes Prime Medicine’s cystic fibrosis prime editing application.
0 · Reply
Knowwtuown
Knowwtuown Aug. 12 at 4:43 PM
$PRME OptiPrime showed extremely encouraging possibilities with the CF program. Probably not going to move the stock much, but this Scientific Development could have a profound impact on Prime. “OptiPrime doubled F508del correction from 11% to 22% after testing only eight AI-selected guides—an optimization that previously took years.” That suggests Prime’s CF program could move faster and require substantially less laboratory screening. But the remaining decisive hurdle is ReCode’s ability to deliver the editor efficiently throughout human airway tissue.
0 · Reply
DOGBIRD
DOGBIRD Aug. 12 at 4:25 PM
$PRME Before OptiPrime: DNA target → design lots of pegRNAs → test them experimentally → find one that works With OptiPrime: DNA target → OptiPrime predicts/designs promising pegRNAs → test the best candidates → much faster optimization So basically AI optimization layer for prime editing that'll cut cost & time?
0 · Reply
ATTAB0Y
ATTAB0Y Aug. 12 at 3:56 PM
1 · Reply
ATTAB0Y
ATTAB0Y Aug. 12 at 3:52 PM
$PRME OptiPrime
0 · Reply
jschor88
jschor88 Aug. 12 at 2:52 PM
$PRME 🚀
0 · Reply
PorkchopSquats
PorkchopSquats Aug. 11 at 10:40 PM
$PRME She’s a grower not a shower.
0 · Reply
LadsAndGents
LadsAndGents Aug. 11 at 5:19 PM
$PRME yay.. 3.60s on the cards
1 · Reply
DOGBIRD
DOGBIRD Aug. 11 at 5:13 PM
$PRME Patiently holding what I already have. Will gladly add more lower or higher once theres some clarity on cash runway.
0 · Reply
Knowwtuown
Knowwtuown Aug. 11 at 5:12 PM
$PRME the most important player at Prime today may be the CFO, Svetlana Makhni. She was also given the responsibility of Corporate Development. If you look at her background she isn’t just a “bean counter”, she is a dealmaker. She did time at Goldman, BMO and Blackstone.
4 · Reply