Market Cap 8.22B
Revenue (ttm) 0.00
Net Income (ttm) -425.38M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 400,900
Avg Vol 581,254
Day's Range N/A - N/A
Shares Out 78.62M
Stochastic %K 42%
Beta 1.15
Analysts Strong Sell
Price Target $142.39

Company Profile

Nuvalent, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are Zidesamtinib (NVL-520), a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung ca...

Industry: Biotechnology
Sector: Healthcare
Phone: 857 357 7000
Address:
One Broadway, 14th Floor, Cambridge, United States
Quantumup
Quantumup May. 5 at 10:35 AM
Citizens reiterated $NUVB Market Outperform; $10, and said: The Ibtrozi launch is progressing in the right direction, with an increasing share of new prescriptions coming from the front-line ROS1+ NSCLC population. $BMY $NUVL PFE RHHBY Citizens added—Over the past three quarters, front-line new patients starts have increased, from 30% to over 50% of Ibtrozi scripts. Based on updated pivotal TRUST-I/II data shared at AACR (our coverage here), with the median duration of response maturing to nearly 50 months, Ibtrozi has increased revenue-generating potential based on revenue stacking. Management noted that revenue-stacking effects were first seen in 1Q26, and as more new starts come from front-line patients this should continue to increase quarter over quarter. Management remains comfortable with the YE26 consensus. We highlight the name, especially given the sell-off after the 4Q25 earnings report, as we are now seeing progress with the launch.
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser May. 4 at 5:01 PM
$NUVL RSI: 44.14, MACD: -0.2214 Vol: 2.88, MA20: 104.15, MA50: 101.85 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
forprofit12
forprofit12 May. 1 at 4:18 PM
$NUVL added. Will add more if it falls
0 · Reply
jayessbee
jayessbee Apr. 30 at 12:28 PM
$NUVL https://www.businesswire.com/news/home/20260430014027/en/Guardant-Health-Announces-Multi-Year-Strategic-Collaboration-with-Nuvalent-to-Develop-Companion-Diagnostics-and-Support-Potential-Commercialization-of-Targeted-Cancer-Therapies-Using-the-Guardant-Infinity-Platform
0 · Reply
Quantumup
Quantumup Apr. 28 at 12:33 PM
H.C. Wainwright reiterated $NUVB Buy; $17, and said: Yesterday, Nuvation announced that IBTROZI (taletrectinib) was added to the National Comprehensive Cancer Network (NCCN) Guidelines for CNS Cancers. $BMY $NUVL PFE RHHBY H.C. Wainwright added—Per the updated guidelines, the NCCN now recommends taletrectinib as a systemic therapy option for ROS1+ NSCLC patients with brain metastases. This recommendation is supported by pooled results from the TRUST-I and TRUST-II trials. In particular, we draw investor attention to the fact that treatment with IBTROZI demonstrated 76.5% and 65.6% intracranial ORRs in TKI-naive and TKI-pretreated patients, respectively. From our perspective, this development is incrementally positive for Nuvation and should provide another tailwind for IBTROZI adoption. Accordingly, we reiterate our Buy rating and 12-month price target of $17 per share.
1 · Reply
Hognose
Hognose Apr. 28 at 8:51 AM
$CAPR $NUVL $ASND $RYTM $ABVX monsters in the making.
0 · Reply
Hognose
Hognose Apr. 24 at 6:24 AM
$NUVL big buy here.
0 · Reply
SuperGreenToday
SuperGreenToday Apr. 21 at 6:50 PM
$NUVL Share Price: $106.65 Contract Selected: Oct 16, 2026 $115 Calls Buy Zone: $7.22 – $8.93 Target Zone: $11.97 – $14.63 Potential Upside: 57% ROI Time to Expiration: 177 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
Coastalcool
Coastalcool Apr. 20 at 10:05 PM
$IOVA I am still a holder here but wondering why the Market is treating $NUVL as the only winner in NSCLC, despite its $8.5 B valuation. Do smart money think $ iova will end up like $REPL re NSCLC ?
Night_Owl_Biotech
Night_Owl_Biotech Apr. 10 at 1:58 AM
For those wondering what will happen to $REPL tomorrow (assuming good news), attached is a list of all 51 new (since 1/1/2017) commercial-stage oncology focused bio's share prices 45, 30 & 7 days before & after announcing FDA approval. We also show the bio's share price as of the close on the day before, the "Day Of" in yellow which is the bio's 1st close after announcing FDA approval & the day after. We exclude $ONC You'll note just over half trade higher after FDA approval & just less than half trade lower. Other oncology focused PDUFA dates nearing; $ARVN $NUVL $CGEM ? The share prices of those who receive CRLs are not included but even a toddler can guess what happens. All the same we track the data so let us know if you'd like us to share (but we'll tell you they all traded meaningfully lower).
3 · Reply
Latest News on NUVL
Nuvalent reports Q1 EPS ($1.39), consensus ($1.31)

2026-05-07T11:04:05.000Z - 6 days ago

Nuvalent reports Q1 EPS ($1.39), consensus ($1.31)


Nuvalent submits neladalkib NDA to FDA

2026-04-07T10:47:34.000Z - 5 weeks ago

Nuvalent submits neladalkib NDA to FDA


Nuvalent initiated with an Overweight at Wells Fargo

2026-03-30T09:30:09.000Z - 6 weeks ago

Nuvalent initiated with an Overweight at Wells Fargo


Nuvalent Transcript: Leerink Global Healthcare Conference 2026

Mar 9, 2026, 2:20 PM EDT - 2 months ago

Nuvalent Transcript: Leerink Global Healthcare Conference 2026


Nuvalent price target raised to $138 from $132 at UBS

2026-03-02T14:12:04.000Z - 2 months ago

Nuvalent price target raised to $138 from $132 at UBS


Nuvalent reports Q4 EPS ($1.58), consensus ($1.44)

2026-02-26T11:51:23.000Z - 2 months ago

Nuvalent reports Q4 EPS ($1.58), consensus ($1.44)


Nuvalent Transcript: 44th Annual J.P. Morgan Healthcare Conference

Jan 13, 2026, 12:00 PM EST - 4 months ago

Nuvalent Transcript: 44th Annual J.P. Morgan Healthcare Conference


Nuvalent files automatic mixed securities shelf

2025-12-22T12:55:23.000Z - 5 months ago

Nuvalent files automatic mixed securities shelf


Nuvalent price target lowered to $145 from $147 at JPMorgan

2025-12-19T12:01:02.000Z - 5 months ago

Nuvalent price target lowered to $145 from $147 at JPMorgan


Nuvalent Appoints Ron Squarer to Board of Directors

Dec 10, 2025, 4:01 PM EST - 5 months ago

Nuvalent Appoints Ron Squarer to Board of Directors


Nuvalent initiated with a Buy at Truist

2025-11-24T12:31:03.000Z - 6 months ago

Nuvalent initiated with a Buy at Truist


Nuvalent 4.95M share Secondary priced at $101.00

2025-11-19T11:15:20.000Z - 6 months ago

Nuvalent 4.95M share Secondary priced at $101.00


Nuvalent Announces Pricing of Public Offering of Common Stock

Nov 18, 2025, 11:50 PM EST - 6 months ago

Nuvalent Announces Pricing of Public Offering of Common Stock


Nuvalent price target raised to $135 from $120 at Goldman Sachs

2025-11-18T14:31:34.000Z - 6 months ago

Nuvalent price target raised to $135 from $120 at Goldman Sachs


Nuvalent price target raised to $155 from $125 at Guggenheim

2025-11-18T12:21:05.000Z - 6 months ago

Nuvalent price target raised to $155 from $125 at Guggenheim


Nuvalent price target raised to $158 from $112 at Baird

2025-11-18T12:20:42.000Z - 6 months ago

Nuvalent price target raised to $158 from $112 at Baird


Nuvalent announces $500M Class A common stock offering

2025-11-17T21:05:14.000Z - 6 months ago

Nuvalent announces $500M Class A common stock offering


Nuvalent Announces Public Offering of Common Stock

Nov 17, 2025, 4:01 PM EST - 6 months ago

Nuvalent Announces Public Offering of Common Stock


Nuvalent price target raised to $152 from $112 at Barclays

2025-11-17T18:30:16.000Z - 6 months ago

Nuvalent price target raised to $152 from $112 at Barclays


Nuvalent Transcript: Study Update

Nov 17, 2025, 8:00 AM EST - 6 months ago

Nuvalent Transcript: Study Update


Nuvalent Transcript: UBS Virtual Oncology Day

Oct 1, 2025, 3:30 PM EDT - 8 months ago

Nuvalent Transcript: UBS Virtual Oncology Day


Nuvalent to Participate in the UBS 2025 Virtual Oncology Day

Sep 24, 2025, 6:30 AM EDT - 8 months ago

Nuvalent to Participate in the UBS 2025 Virtual Oncology Day


Nuvalent Transcript: Cantor Global Healthcare Conference 2025

Sep 4, 2025, 9:45 AM EDT - 8 months ago

Nuvalent Transcript: Cantor Global Healthcare Conference 2025


Nuvalent Transcript: Investor Update

Jun 24, 2025, 8:00 AM EDT - 11 months ago

Nuvalent Transcript: Investor Update


Nuvalent Appoints Christy Oliger to Board of Directors

Jun 18, 2025, 4:30 PM EDT - 11 months ago

Nuvalent Appoints Christy Oliger to Board of Directors


Nuvalent Appoints Grant Bogle to Board of Directors

Dec 9, 2024, 6:30 AM EST - 1 year ago

Nuvalent Appoints Grant Bogle to Board of Directors


Nuvalent Transcript: Stifel 2024 Healthcare Conference

Nov 19, 2024, 3:35 PM EST - 1 year ago

Nuvalent Transcript: Stifel 2024 Healthcare Conference


Cancer Biotech Nuvalent's Stock Jumps on Positive Data

Sep 16, 2024, 11:18 AM EDT - 1 year ago

Cancer Biotech Nuvalent's Stock Jumps on Positive Data


Quantumup
Quantumup May. 5 at 10:35 AM
Citizens reiterated $NUVB Market Outperform; $10, and said: The Ibtrozi launch is progressing in the right direction, with an increasing share of new prescriptions coming from the front-line ROS1+ NSCLC population. $BMY $NUVL PFE RHHBY Citizens added—Over the past three quarters, front-line new patients starts have increased, from 30% to over 50% of Ibtrozi scripts. Based on updated pivotal TRUST-I/II data shared at AACR (our coverage here), with the median duration of response maturing to nearly 50 months, Ibtrozi has increased revenue-generating potential based on revenue stacking. Management noted that revenue-stacking effects were first seen in 1Q26, and as more new starts come from front-line patients this should continue to increase quarter over quarter. Management remains comfortable with the YE26 consensus. We highlight the name, especially given the sell-off after the 4Q25 earnings report, as we are now seeing progress with the launch.
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser May. 4 at 5:01 PM
$NUVL RSI: 44.14, MACD: -0.2214 Vol: 2.88, MA20: 104.15, MA50: 101.85 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
forprofit12
forprofit12 May. 1 at 4:18 PM
$NUVL added. Will add more if it falls
0 · Reply
jayessbee
jayessbee Apr. 30 at 12:28 PM
$NUVL https://www.businesswire.com/news/home/20260430014027/en/Guardant-Health-Announces-Multi-Year-Strategic-Collaboration-with-Nuvalent-to-Develop-Companion-Diagnostics-and-Support-Potential-Commercialization-of-Targeted-Cancer-Therapies-Using-the-Guardant-Infinity-Platform
0 · Reply
Quantumup
Quantumup Apr. 28 at 12:33 PM
H.C. Wainwright reiterated $NUVB Buy; $17, and said: Yesterday, Nuvation announced that IBTROZI (taletrectinib) was added to the National Comprehensive Cancer Network (NCCN) Guidelines for CNS Cancers. $BMY $NUVL PFE RHHBY H.C. Wainwright added—Per the updated guidelines, the NCCN now recommends taletrectinib as a systemic therapy option for ROS1+ NSCLC patients with brain metastases. This recommendation is supported by pooled results from the TRUST-I and TRUST-II trials. In particular, we draw investor attention to the fact that treatment with IBTROZI demonstrated 76.5% and 65.6% intracranial ORRs in TKI-naive and TKI-pretreated patients, respectively. From our perspective, this development is incrementally positive for Nuvation and should provide another tailwind for IBTROZI adoption. Accordingly, we reiterate our Buy rating and 12-month price target of $17 per share.
1 · Reply
Hognose
Hognose Apr. 28 at 8:51 AM
$CAPR $NUVL $ASND $RYTM $ABVX monsters in the making.
0 · Reply
Hognose
Hognose Apr. 24 at 6:24 AM
$NUVL big buy here.
0 · Reply
SuperGreenToday
SuperGreenToday Apr. 21 at 6:50 PM
$NUVL Share Price: $106.65 Contract Selected: Oct 16, 2026 $115 Calls Buy Zone: $7.22 – $8.93 Target Zone: $11.97 – $14.63 Potential Upside: 57% ROI Time to Expiration: 177 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
Coastalcool
Coastalcool Apr. 20 at 10:05 PM
$IOVA I am still a holder here but wondering why the Market is treating $NUVL as the only winner in NSCLC, despite its $8.5 B valuation. Do smart money think $ iova will end up like $REPL re NSCLC ?
Night_Owl_Biotech
Night_Owl_Biotech Apr. 10 at 1:58 AM
For those wondering what will happen to $REPL tomorrow (assuming good news), attached is a list of all 51 new (since 1/1/2017) commercial-stage oncology focused bio's share prices 45, 30 & 7 days before & after announcing FDA approval. We also show the bio's share price as of the close on the day before, the "Day Of" in yellow which is the bio's 1st close after announcing FDA approval & the day after. We exclude $ONC You'll note just over half trade higher after FDA approval & just less than half trade lower. Other oncology focused PDUFA dates nearing; $ARVN $NUVL $CGEM ? The share prices of those who receive CRLs are not included but even a toddler can guess what happens. All the same we track the data so let us know if you'd like us to share (but we'll tell you they all traded meaningfully lower).
3 · Reply
Quantumup
Quantumup Apr. 8 at 1:27 PM
Truist reiterated $NUVB Buy; $12, and said: Ibtrozi Momentum Builds; Safu's Glioma Prevalence Oppty Underappreciated $BMY RHHBY PFE $NUVL Truist added—We hosted CFO Philippe Sauvage & Corp Dev/IR Head JR DeVita for meetings in Chicago yesterday. Key takeaways: (1) Ibtrozi launch is off to a strong start with potential to add ~200 pts/qtr near term; (2) Pt mix is gradually shifting toward 1L use, supporting the stacking effect; (3) ROS1 market remains underpenetrated with potential to expand with more testing; (4) clarity on competitive dynamics with zidesamtinib will emerge once both agents are in the same settings; (5) safu's oppty in glioma is prevalence-driven & larger than anticipated. Collectively, we come away constructive on the ROS1 launch and safu's longer-term glioma potential - Reiterate Buy on NUVB.
0 · Reply
SilverEagle
SilverEagle Apr. 2 at 5:11 PM
$NUVL setting up nicely and attempting to reclaim its weekly 10/20.
0 · Reply
NorthStarStats
NorthStarStats Apr. 2 at 1:42 AM
Output from a custom NorthStarStats momentum scanner highlighting stocks with strengthening price structure and momentum. Setups to watch and study — not trade recommendations. $WAB Score 100, $NUVL Score 98, $OMER Score 98, $HCM Score 98, $ZLAB Score 98
0 · Reply
NorthStarStats
NorthStarStats Apr. 1 at 1:45 AM
Output from a custom NorthStarStats momentum scanner highlighting stocks with strengthening price structure and momentum. Setups to watch and study — not trade recommendations. $CSX Score 100, $NUVL Score 100, $AZN Score 100, $WAB Score 100, $PCVX Score 98
0 · Reply
Quantumup
Quantumup Mar. 31 at 12:19 PM
Stifel reiterated $NUVL Buy/$135, and said—Last week, we hosted a series of investor meetings with Jim Porter (CEO) and Alex Balcom (CFO) from Nuvalent (NUVL). $PFE RHHBY TAK NVS $NUVB Stifel added—Main takeaways: Investors felt management sounded solid on expectations for the ROS1 launch later this year. Clinical data at AACR should provide additional insight into zidesamtinib durability in more heavily pre-treated patients. Neladalkib NDA filing is on track for 1H26, management seems confident that data package will support a 2L label. Enrollment is strong in the global EAPs - patients only need 1 prior TKI to enroll (e.g., prior lorlatinib for ALK+ or taletrectinib for ROS1+ is not required). While investors await the launches and are eager for more clarity on catalyst cadence, management implies the NUVL story could be far from boring; they have an abundance of clinical data (including in ROS1, ALK, HER2 NSCLC) that could be presented at future medical meetings.
0 · Reply
jayessbee
jayessbee Mar. 11 at 9:12 PM
Entered $NUVL today @ 99.84. Appreciate the insights shared by several folks in here-- lots of noise, but good nuggets in between. GLTA
0 · Reply
Coastalcool
Coastalcool Mar. 6 at 5:28 PM
$IOVA You can tell that it doesn’t take much to become an analyst nowadays. The analyst at UVS raised the price target for $IOVA from $2 to $4 how genius of him . They just heard the management projecting future annual earnings in excess of $10 billion and succeeding in the first year of commercialisation building all own facilities and infrastructures. The asset of this company is basically evolution’s way of fighting the cancer using the technology to enhance it billion times t won’t be too long from here to see $IOVA dominate the solid cancer field. lowest Mc of 2000,000,000s whereas $$NUVL , holding the NDAon NSCLC at aluation of 8,000,000,000+ while Ivan has the best in class data To date. Beside. $NUVL has yet to prove that Works some varieties of cancers.
1 · Reply
justiceforb_85
justiceforb_85 Mar. 5 at 11:33 PM
$NUVL added. Look forward to PDUFA and announcement of new drug candidate.
0 · Reply
IN0V8
IN0V8 Mar. 3 at 6:27 PM
$NUVL 3/2 BUy UBS raises target price to $138 from $132
0 · Reply
Quantumup
Quantumup Mar. 3 at 12:43 PM
Citizens reiterated $NUVB Market Outperform/$100 $NUVL $BMY - $ZLAB $PFE RHHBY Citizens said: Nuvation Bio continues to execute on the Ibtrozi launch, with 216 new patients started in 4Q25 and $15.7M in Ibtrozi net product value. Overall, we await penetration into front-line patients to see the effect of long-duration treatment play out and transform into sales. The company's cash balance was $529.2M, and OpEx was $76.2M and $266.7M, respectively, for 4Q25 and FY25. Management expects its cash runway to last until NUVB is cash flow positive. We maintain our Market Outperform rating and $10 DCF-derived price target.
0 · Reply
justiceforb_85
justiceforb_85 Feb. 28 at 2:30 AM
$NUVL low volume. Hopefully will continue to go up as PDUFA approaches and new candidate is disclosed.
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser Feb. 27 at 4:33 PM
$NUVL RSI: 44.57, MACD: -0.2291 Vol: 1.72, MA20: 103.09, MA50: 103.44 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply