Market Cap 466.43M
Revenue (ttm) 0.00
Net Income (ttm) -74.88M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 598,600
Avg Vol 987,958
Day's Range N/A - N/A
Shares Out 66.63M
Stochastic %K 17%
Beta 3.02
Analysts Strong Sell
Price Target $18.90

Company Profile

Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers programs for the treatment of diamond-blackfan anemia, Bone Marrow Fa...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 651 8851
Address:
26 Landsdowne Street, Cambridge, United States
DonCorleone77
DonCorleone77 May. 10 at 3:41 PM
$FULC Fulcrum Therapeutics price target raised to $8 from $7 at BofA BofA raised the firm's price target on Fulcrum Therapeutics to $8 from $7 and keeps an Underperform rating on the shares. The firm updated the company's model post the Q1 report.
0 · Reply
momyurich
momyurich May. 4 at 5:51 PM
$FULC 📈🤝⏳🧐📈
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser May. 4 at 1:58 PM
$FULC RSI: 45.86, MACD: -0.1236 Vol: 0.32, MA20: 7.74, MA50: 7.75 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
PenkeInvesting
PenkeInvesting Apr. 28 at 4:34 PM
Fundamental analysis of $FULC (Fulcrum Therapeutics, Inc.) based on financial data and reported results. #FULC #Fulcrum
0 · Reply
EarningsCentral
EarningsCentral Apr. 28 at 1:13 PM
$FULC Fulcrum Therapeutics Q1 2026 Earnings | Why Pociredir Could Transform Sickle Cell Treatment https://youtu.be/49NVVYIl7vM
0 · Reply
momyurich
momyurich Apr. 27 at 4:33 PM
$FULC 🎯📈👍
0 · Reply
StocktwitsEarnings
StocktwitsEarnings Apr. 27 at 12:22 PM
$FULC Q1 '26 Earnings Results & Recap • Reported GAAP EPS of -$0.25 up 10.71% YoY • Fulcrum Therapeutics expects existing cash, cash equivalents, and marketable securities of $333.3 million as of March 31, 2026, to fund operating expenses and capital expenditures into 2029. The company also plans to provide next trial design details in Q2 2026.
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DonCorleone77
DonCorleone77 Apr. 27 at 11:33 AM
$FULC Fulcrum Therapeutics CFO Alan Musso to retire CFO Alan Musso plans to retire later this year to spend more time with his family and other outside interests. Musso will remain in his role until a successor is named and has agreed to serve as a consultant thereafter to support a transition. Fulcrum will initiate a search to identify a successor.
0 · Reply
DonCorleone77
DonCorleone77 Apr. 27 at 11:27 AM
$FULC Fulcrum Therapeutics reports Q1 EPS (25c), consensus (30c) As of March 31, cash, cash equivalents, and marketable securities were $333.3M, compared to $352.3M as of December 31, 2025. The decrease of $19M was primarily due to cash used to fund operating activities in 2026. "The strength of the clinical data presented in the first quarter further reinforce our conviction in pociredir's potential to address the underlying biology of sickle cell disease," said Alex Sapir, Fulcrum's president and CEO. "The magnitude of HbF induction and improvements in markers of hemolysis and anemia observed to date support our upcoming discussions with the FDA as we prepare for a potential registration-enabling study in the second half of 2026. With a strong balance sheet extending our cash runway into 2029, we are well positioned to advance pociredir through the next phase of clinical development."
0 · Reply
Delorianskyfighter
Delorianskyfighter Apr. 26 at 8:17 PM
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Latest News on FULC
Fulcrum Therapeutics Earnings Call Transcript: Q1 2026

Apr 27, 2026, 8:00 AM EDT - 16 days ago

Fulcrum Therapeutics Earnings Call Transcript: Q1 2026


Fulcrum Therapeutics reports Q1 EPS (25c), consensus (30c)

2026-04-27T11:56:41.000Z - 16 days ago

Fulcrum Therapeutics reports Q1 EPS (25c), consensus (30c)


Fulcrum Therapeutics CFO Alan Musso to retire

2026-04-27T11:56:23.000Z - 16 days ago

Fulcrum Therapeutics CFO Alan Musso to retire


Fulcrum Therapeutics move lower ‘overdone,’ says Stifel

2026-02-24T15:27:10.000Z - 2 months ago

Fulcrum Therapeutics move lower ‘overdone,’ says Stifel


Truist remain buyers of Fulcrum Therapeutics shares on weakness

2026-02-24T15:01:25.000Z - 2 months ago

Truist remain buyers of Fulcrum Therapeutics shares on weakness


Fulcrum Therapeutics Earnings Call Transcript: Q4 2025

Feb 24, 2026, 8:00 AM EST - 2 months ago

Fulcrum Therapeutics Earnings Call Transcript: Q4 2025


Fulcrum Therapeutics reports Q4 EPS (31c), consensus (30c)

2026-02-24T12:21:04.000Z - 2 months ago

Fulcrum Therapeutics reports Q4 EPS (31c), consensus (30c)


Fulcrum Therapeutics initiated with an Overweight at JPMorgan

2026-01-12T11:22:01.000Z - 4 months ago

Fulcrum Therapeutics initiated with an Overweight at JPMorgan


Fulcrum Therapeutics 11.85M share Secondary priced at $13.50

2025-12-10T13:00:40.000Z - 5 months ago

Fulcrum Therapeutics 11.85M share Secondary priced at $13.50


Fulcrum Therapeutics price target raised to $7 from $6 at BofA

2025-12-09T14:10:24.000Z - 5 months ago

Fulcrum Therapeutics price target raised to $7 from $6 at BofA


Fulcrum Therapeutics announces $150M offering of common stock

2025-12-08T21:21:50.000Z - 5 months ago

Fulcrum Therapeutics announces $150M offering of common stock


Fulcrum Therapeutics Transcript: Status Update

Dec 7, 2025, 7:00 AM EST - 5 months ago

Fulcrum Therapeutics Transcript: Status Update


Fulcrum Therapeutics Earnings Call Transcript: Q3 2025

Oct 29, 2025, 8:00 AM EDT - 7 months ago

Fulcrum Therapeutics Earnings Call Transcript: Q3 2025


Fulcrum Therapeutics to Present at Upcoming Investor Meetings

Aug 26, 2025, 8:00 AM EDT - 9 months ago

Fulcrum Therapeutics to Present at Upcoming Investor Meetings


Fulcrum Therapeutics to Present at Upcoming Medical Meetings

May 29, 2025, 4:10 PM EDT - 1 year ago

Fulcrum Therapeutics to Present at Upcoming Medical Meetings


Fulcrum Therapeutics Earnings Call Transcript: Q1 2025

May 1, 2025, 8:00 AM EDT - 1 year ago

Fulcrum Therapeutics Earnings Call Transcript: Q1 2025


Fulcrum Therapeutics Earnings Call Transcript: Q4 2024

Feb 25, 2025, 8:00 AM EST - 1 year ago

Fulcrum Therapeutics Earnings Call Transcript: Q4 2024


Fulcrum Therapeutics Earnings Call Transcript: Q3 2024

Nov 13, 2024, 8:00 AM EST - 1 year ago

Fulcrum Therapeutics Earnings Call Transcript: Q3 2024


DonCorleone77
DonCorleone77 May. 10 at 3:41 PM
$FULC Fulcrum Therapeutics price target raised to $8 from $7 at BofA BofA raised the firm's price target on Fulcrum Therapeutics to $8 from $7 and keeps an Underperform rating on the shares. The firm updated the company's model post the Q1 report.
0 · Reply
momyurich
momyurich May. 4 at 5:51 PM
$FULC 📈🤝⏳🧐📈
0 · Reply
OfficialStocktwitsUser
OfficialStocktwitsUser May. 4 at 1:58 PM
$FULC RSI: 45.86, MACD: -0.1236 Vol: 0.32, MA20: 7.74, MA50: 7.75 🔴 SELL - Downtrend 👉 https://quantumstockalerts.com Disclaimer: I am not a financial advisor. This post reflects personal analysis and opinions only. Please do your own research before investing or trading.
0 · Reply
PenkeInvesting
PenkeInvesting Apr. 28 at 4:34 PM
Fundamental analysis of $FULC (Fulcrum Therapeutics, Inc.) based on financial data and reported results. #FULC #Fulcrum
0 · Reply
EarningsCentral
EarningsCentral Apr. 28 at 1:13 PM
$FULC Fulcrum Therapeutics Q1 2026 Earnings | Why Pociredir Could Transform Sickle Cell Treatment https://youtu.be/49NVVYIl7vM
0 · Reply
momyurich
momyurich Apr. 27 at 4:33 PM
$FULC 🎯📈👍
0 · Reply
StocktwitsEarnings
StocktwitsEarnings Apr. 27 at 12:22 PM
$FULC Q1 '26 Earnings Results & Recap • Reported GAAP EPS of -$0.25 up 10.71% YoY • Fulcrum Therapeutics expects existing cash, cash equivalents, and marketable securities of $333.3 million as of March 31, 2026, to fund operating expenses and capital expenditures into 2029. The company also plans to provide next trial design details in Q2 2026.
0 · Reply
DonCorleone77
DonCorleone77 Apr. 27 at 11:33 AM
$FULC Fulcrum Therapeutics CFO Alan Musso to retire CFO Alan Musso plans to retire later this year to spend more time with his family and other outside interests. Musso will remain in his role until a successor is named and has agreed to serve as a consultant thereafter to support a transition. Fulcrum will initiate a search to identify a successor.
0 · Reply
DonCorleone77
DonCorleone77 Apr. 27 at 11:27 AM
$FULC Fulcrum Therapeutics reports Q1 EPS (25c), consensus (30c) As of March 31, cash, cash equivalents, and marketable securities were $333.3M, compared to $352.3M as of December 31, 2025. The decrease of $19M was primarily due to cash used to fund operating activities in 2026. "The strength of the clinical data presented in the first quarter further reinforce our conviction in pociredir's potential to address the underlying biology of sickle cell disease," said Alex Sapir, Fulcrum's president and CEO. "The magnitude of HbF induction and improvements in markers of hemolysis and anemia observed to date support our upcoming discussions with the FDA as we prepare for a potential registration-enabling study in the second half of 2026. With a strong balance sheet extending our cash runway into 2029, we are well positioned to advance pociredir through the next phase of clinical development."
0 · Reply
Delorianskyfighter
Delorianskyfighter Apr. 26 at 8:17 PM
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zerodayrounder
zerodayrounder Apr. 15 at 7:36 PM
$SPRO just went back and looked -- Esther is not a public company biotech CEO imo -- she spent ~20 years covering biotech as sell-side analyst. Hired as $FULC CFO in January 2022 --- FULC founder came back in January 2023, then FULC raised $125 million few weeks later, then their sickle cell drug candidate got bad news in Feb 2023 and the stock got crushed -- Esther resigns from FULC in April 2023 (pushed out by founder/Board?). Hired as SPRO CFO in November 2023 -- takes interim then permanent title after Ankit/Shay have their problems in 2024/2025. Esther is a care-taker CEO --- if anything happens with "SPRO 2.0" and selling tebi and reorienting SPRO into a growth biotech again -- it will be with a new CEO running the show. I'm pretty certain of that.
2 · Reply
SuperGreenToday
SuperGreenToday Mar. 23 at 9:11 PM
$FULC Share Price: $6.89 Contract Selected: Jan 15, 2027 $5 Calls Buy Zone: $1.36 – $1.68 Target Zone: $2.55 – $3.12 Potential Upside: 77% ROI Time to Expiration: 297 Days | Updates via https://fxcapta.com/stockinfo/
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BKronic5
BKronic5 Mar. 23 at 2:41 PM
$FULC 16.47 down to 6.09. Why can’t this thing just push once and for all
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Merlintrader
Merlintrader Mar. 19 at 2:43 PM
$FULC https://www.merlintrader.com/fulcrum-therapeutics-inc-dd-march19/
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DARKP00L
DARKP00L Mar. 19 at 12:30 PM
$FULC 08:26 on Mar. 19 2026 MedicAlert Foundation, SCDAA And Fulcrum Therapeutics Partner To Help Streamline And Expedite ED Care For People Living With Sickle Cell Disease Through Rapid Access To Patient-Specific Care Plans #tradeideas
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Yi_YandH
Yi_YandH Mar. 15 at 8:34 PM
$FULC &. $ICU
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elmono
elmono Mar. 2 at 3:29 PM
$FULC junk
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Jack_Nicholson_Truth
Jack_Nicholson_Truth Feb. 25 at 3:16 PM
$FULC let's go back to 11 after that dumb drop. If 20%, fulc would be $25 now. 19.4% is $8.50 with $5 in cash. 100% premium to buy fulc now would be $18 or $1.2B to get the most advanced oral pill for sickle cell. Shake out retail first. Then climb to where the offering was at $13.50 as fda meeting minutes come out. The ceo wants to cash out and not do P3 imho
1 · Reply
Jack_Nicholson_Truth
Jack_Nicholson_Truth Feb. 24 at 8:17 PM
$FULC OK I bought more. Active oral drug with 380m cash and 580m market cap now. CEO wants to sell and partner. If you can wait a few days we might have another ocul situation where the dip is bought up. Fulc only at 3.5m volume and lots of funds involved. Risk vs reward
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Spenny777
Spenny777 Feb. 24 at 7:47 PM
$FULC bought more at 8.87, thanks! Let's
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d_risk
d_risk Feb. 24 at 6:00 PM
$FULC - Fulcrum Therapeutics Inc - 10K - Updated Risk Factors FULC’s risk profile now emphasizes ongoing development and early Phase 1b experience with pociredir in SCD, new tax uncertainty from the 2025 One Big Beautiful Bill Act and a deemed Section 382 ownership change, added exposure to evolving global privacy/biometric and data-transfer laws, heightened AI-related cybersecurity and compliance risks, IRA/MFN-style drug pricing pressure, FDA staffing and policy instability, and the end of its MyoKardia collaboration, while legacy losmapimod/FSHD and CAMP4 risks recede. #Biopharmaceuticals #DrugDevelopment #RegulatoryRisk #DataPrivacy #DrugPricingPressure 🟢 Added 🟠 Removed https://d-risk.ai/FULC/10-K/2026-02-24
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Quantumup
Quantumup Feb. 24 at 4:29 PM
Stifel reiterated $FULC Buy/$25 and said it thinks the Market is Splitting Hairs & Misses the Bigger Picture. $CRPR - VRTX $NVO $AGIO $BEAM Oppenheimer reiterated FULC Outperform; $15 PT, and said, We Think FULC Shares are Trading Down Today Because of Profit-Taking. Here's what else Stifel and Oppenheimer had to say: https://x.com/Quantumup1/status/2026332962359263672?s=20
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