Market Cap 3.89B
Revenue (ttm) 0.00
Net Income (ttm) -512.54M
EPS (ttm) N/A
PE Ratio 0.00
Forward PE N/A
Profit Margin 0.00%
Debt to Equity Ratio 0.00
Volume 1,099,600
Avg Vol 1,778,454
Day's Range N/A - N/A
Shares Out 159.85M
Stochastic %K 17%
Beta 1.01
Analysts Strong Sell
Price Target $35.31

Company Profile

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement thera...

Industry: Biotechnology
Sector: Healthcare
Phone: 650 866 8547
Address:
161 Oyster Point Boulevard, South San Francisco, United States
steven1x
steven1x Aug. 18 at 6:24 PM
$DNLI what did AI miss? https://g.co/gemini/share/60e24f1bed3e
0 · Reply
Estimize
Estimize Aug. 13 at 8:03 PM
Wall St is expecting -0.39 EPS for $DNLI Q3 [Reporting 11/11 AMC] http://www.estimize.com/intro/dnli?chart=historical&metric_name=eps&utm_c
0 · Reply
GoAt2OG
GoAt2OG Aug. 13 at 2:47 PM
$DNLI started off with 750 commons here; let’s see how this moves along
0 · Reply
GoAt2OG
GoAt2OG Aug. 13 at 11:12 AM
$DNLI looking to start a position here; fishing 🎣
0 · Reply
prismmarketview
prismmarketview Aug. 10 at 1:34 PM
(NASDAQ: $DNLI ) Denali Therapeutics believes improving how medicines are delivered across the blood-brain barrier could unlock better outcomes in Alzheimer's disease. With two clinical-stage Alzheimer's programs now advancing and initial human data expected in 2027, investors are increasingly watching whether Denali's proprietary TransportVehicle™ platform can translate promising science into clinical results. https://prismmarketview.com/denali-bets-better-brain-distribution-could-shape-the-next-generation-of-alzheimers-therapies/
0 · Reply
stockpicker63
stockpicker63 Aug. 9 at 3:11 PM
$DNLI — TA + AI Analysis (Short-Term Bullish Setup)
0 · Reply
dgbio
dgbio Aug. 7 at 1:41 AM
$DNLI Orphan Drug designation just received for the FTD-GRN program.
0 · Reply
dgbio
dgbio Aug. 7 at 12:30 AM
$DNLI Guidance for Q3 revenue is 10-12 million, 2x consensus of 5.5 million.
0 · Reply
JFDI
JFDI Aug. 6 at 11:04 PM
$DNLI Weekly base
0 · Reply
EarningsInsider
EarningsInsider Aug. 6 at 10:01 PM
https://www.marketbeat.com/earnings/reports/2026-8-6-denali-therapeutics-inc-stock/ $DNLI Denali Therapeutics Earnings Transcript
0 · Reply
Latest News on DNLI
Denali Therapeutics Earnings Call Transcript: Q2 2026

Aug 6, 2026, 4:30 PM EDT - 12 days ago

Denali Therapeutics Earnings Call Transcript: Q2 2026


Denali Therapeutics Quarterly report: Q2 2026

Aug 6, 2026, 4:30 PM EDT - 12 days ago

Denali Therapeutics Quarterly report: Q2 2026


Denali Therapeutics Earnings release: Q2 2026

Aug 6, 2026, 4:30 PM EDT - 12 days ago

Denali Therapeutics Earnings release: Q2 2026


Denali Therapeutics reports Q2 EPS (68c), consensus (47c)

2026-08-06T20:11:31.000Z - 12 days ago

Denali Therapeutics reports Q2 EPS (68c), consensus (47c)


Denali Therapeutics falls -14.1%

2026-07-14T16:05:47.000Z - 5 weeks ago

Denali Therapeutics falls -14.1%


Denali Therapeutics falls -12.4%

2026-07-14T14:05:10.000Z - 5 weeks ago

Denali Therapeutics falls -12.4%


Denali Therapeutics resumed with an Overweight at JPMorgan

2026-07-13T09:50:38.000Z - 5 weeks ago

Denali Therapeutics resumed with an Overweight at JPMorgan


Denali Therapeutics Transcript: AGM 2026

Jun 3, 2026, 1:00 PM EDT - 2 months ago

Denali Therapeutics Transcript: AGM 2026


Denali Therapeutics trading resumes

2026-05-21T22:35:11.000Z - 3 months ago

Denali Therapeutics trading resumes


Denali Therapeutics trading halted, news pending

2026-05-21T21:55:12.000Z - 3 months ago

Denali Therapeutics trading halted, news pending


Denali Therapeutics Slides: Corporate presentation

May 12, 2026, 4:00 PM EDT - 3 months ago

Denali Therapeutics Slides: Corporate presentation


Denali Therapeutics Quarterly report: Q1 2026

May 7, 2026, 7:00 AM EDT - 3 months ago

Denali Therapeutics Quarterly report: Q1 2026


Denali Therapeutics Earnings release: Q1 2026

May 7, 2026, 7:00 AM EDT - 3 months ago

Denali Therapeutics Earnings release: Q1 2026


Denali Therapeutics Proxy statement: Proxy filing

Apr 21, 2026, 8:00 AM EDT - 4 months ago

Denali Therapeutics Proxy statement: Proxy filing


Denali Therapeutics Proxy statement: Proxy filing

Apr 21, 2026, 8:00 AM EDT - 4 months ago

Denali Therapeutics Proxy statement: Proxy filing


Denali Therapeutics Transcript: Study update

Mar 25, 2026, 12:30 PM EDT - 5 months ago

Denali Therapeutics Transcript: Study update


Denali Therapeutics Press release: Study update

Mar 25, 2026, 12:30 PM EDT - 5 months ago

Denali Therapeutics Press release: Study update


Denali Therapeutics Slides: Study update

Mar 25, 2026, 12:30 PM EDT - 5 months ago

Denali Therapeutics Slides: Study update


Denali Therapeutics Transcript: Stifel 2026 Virtual CNS Forum

Mar 17, 2026, 2:00 PM EDT - 5 months ago

Denali Therapeutics Transcript: Stifel 2026 Virtual CNS Forum


Denali Therapeutics Earnings release: Q4 2025

Feb 26, 2026, 7:00 AM EST - 6 months ago

Denali Therapeutics Earnings release: Q4 2025


Denali Therapeutics Annual report: Q4 2025

Feb 26, 2026, 7:00 AM EST - 6 months ago

Denali Therapeutics Annual report: Q4 2025


Denali Therapeutics Transcript: Study update

Feb 5, 2026, 3:30 PM EST - 6 months ago

Denali Therapeutics Transcript: Study update


Denali Therapeutics Press release: Study update

Feb 5, 2026, 3:30 PM EST - 6 months ago

Denali Therapeutics Press release: Study update


Denali Therapeutics Slides: Study update

Feb 5, 2026, 3:30 PM EST - 6 months ago

Denali Therapeutics Slides: Study update


Denali Therapeutics Transcript: Investor Day 2025

Dec 4, 2025, 8:30 AM EST - 9 months ago

Denali Therapeutics Transcript: Investor Day 2025


Denali Therapeutics Slides: FY 2025

Dec 4, 2025, 8:30 AM EST - 9 months ago

Denali Therapeutics Slides: FY 2025


Denali Therapeutics Earnings release: Q3 2025

Nov 6, 2025, 7:00 AM EST - 10 months ago

Denali Therapeutics Earnings release: Q3 2025


Denali Therapeutics Quarterly report: Q3 2025

Nov 6, 2025, 7:00 AM EST - 10 months ago

Denali Therapeutics Quarterly report: Q3 2025


Denali Therapeutics Slides: Corporate Presentation

Nov 5, 2025, 6:00 PM EST - 10 months ago

Denali Therapeutics Slides: Corporate Presentation


The Best Small-Cap Stocks to Buy Now

Aug 12, 2025, 9:47 AM EDT - 1 year ago

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Denali Therapeutics Quarterly report: Q2 2025

Aug 11, 2025, 4:00 PM EDT - 1 year ago

Denali Therapeutics Quarterly report: Q2 2025


Denali Therapeutics Earnings release: Q2 2025

Aug 11, 2025, 4:00 PM EDT - 1 year ago

Denali Therapeutics Earnings release: Q2 2025


Denali Therapeutics Slides: Corporate Presentation

May 13, 2025, 7:00 AM EDT - 1 year ago

Denali Therapeutics Slides: Corporate Presentation


Denali Therapeutics Quarterly report: Q1 2025

May 6, 2025, 4:00 PM EDT - 1 year ago

Denali Therapeutics Quarterly report: Q1 2025


Denali Therapeutics Earnings release: Q1 2025

May 6, 2025, 4:00 PM EDT - 1 year ago

Denali Therapeutics Earnings release: Q1 2025


Denali Therapeutics Proxy statement: Proxy Filing

Apr 17, 2025, 8:00 AM EDT - 1 year ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Proxy statement: Proxy Filing

Apr 17, 2025, 8:00 AM EDT - 1 year ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Transcript: Stifel 2025 Virtual CNS Forum

Mar 18, 2025, 2:30 PM EDT - 1 year ago

Denali Therapeutics Transcript: Stifel 2025 Virtual CNS Forum


Denali Therapeutics Slides: FY 2025

Mar 18, 2025, 2:30 PM EDT - 1 year ago

Denali Therapeutics Slides: FY 2025


Denali Therapeutics Transcript: UBS Virtual CNS Day 2025

Mar 17, 2025, 12:00 PM EDT - 1 year ago

Denali Therapeutics Transcript: UBS Virtual CNS Day 2025


Denali Therapeutics Earnings release: Q4 2024

Feb 27, 2025, 4:00 PM EST - 1 year ago

Denali Therapeutics Earnings release: Q4 2024


Denali Therapeutics Annual report: Q4 2024

Feb 27, 2025, 4:00 PM EST - 1 year ago

Denali Therapeutics Annual report: Q4 2024


Denali Therapeutics Slides: FY 2025

Jan 14, 2025, 2:15 PM EST - 1 year ago

Denali Therapeutics Slides: FY 2025


Denali Therapeutics ALS drug fails in mid-stage trial

Jan 6, 2025, 4:43 PM EST - 1 year ago

Denali Therapeutics ALS drug fails in mid-stage trial


Denali Therapeutics Quarterly report: Q3 2024

Nov 5, 2024, 6:00 PM EST - 1 year ago

Denali Therapeutics Quarterly report: Q3 2024


Denali Therapeutics Earnings release: Q3 2024

Nov 5, 2024, 6:00 PM EST - 1 year ago

Denali Therapeutics Earnings release: Q3 2024


Denali Therapeutics Quarterly report: Q2 2024

Aug 1, 2024, 7:00 AM EDT - 2 years ago

Denali Therapeutics Quarterly report: Q2 2024


Denali Therapeutics Earnings release: Q2 2024

Aug 1, 2024, 7:00 AM EDT - 2 years ago

Denali Therapeutics Earnings release: Q2 2024


Denali Therapeutics Slides: Corporate Presentation

May 14, 2024, 7:00 AM EDT - 2 years ago

Denali Therapeutics Slides: Corporate Presentation


Denali Therapeutics Quarterly report: Q1 2024

May 7, 2024, 4:00 PM EDT - 2 years ago

Denali Therapeutics Quarterly report: Q1 2024


Denali Therapeutics Earnings release: Q1 2024

May 7, 2024, 4:00 PM EDT - 2 years ago

Denali Therapeutics Earnings release: Q1 2024


Denali Therapeutics Proxy statement: Proxy Filing

Apr 18, 2024, 8:00 AM EDT - 2 years ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Proxy statement: Proxy Filing

Apr 18, 2024, 8:00 AM EDT - 2 years ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Annual report: Q4 2023

Feb 27, 2024, 7:00 AM EST - 2 years ago

Denali Therapeutics Annual report: Q4 2023


Denali Therapeutics Earnings release: Q4 2023

Feb 27, 2024, 7:00 AM EST - 2 years ago

Denali Therapeutics Earnings release: Q4 2023


Denali Therapeutics Quarterly report: Q3 2023

Nov 7, 2023, 4:00 PM EST - 3 years ago

Denali Therapeutics Quarterly report: Q3 2023


Denali Therapeutics Earnings release: Q3 2023

Nov 7, 2023, 4:00 PM EST - 3 years ago

Denali Therapeutics Earnings release: Q3 2023


Denali Therapeutics Slides: FY 2023

Sep 12, 2023, 11:30 AM EDT - 3 years ago

Denali Therapeutics Slides: FY 2023


Denali Therapeutics Quarterly report: Q2 2023

Aug 8, 2023, 4:00 PM EDT - 3 years ago

Denali Therapeutics Quarterly report: Q2 2023


Denali Therapeutics Earnings release: Q2 2023

Aug 8, 2023, 4:00 PM EDT - 3 years ago

Denali Therapeutics Earnings release: Q2 2023


Denali Therapeutics Transcript: Study Result

Jun 20, 2023, 8:30 AM EDT - 3 years ago

Denali Therapeutics Transcript: Study Result


Denali Therapeutics Press release: Study Result

Jun 20, 2023, 8:30 AM EDT - 3 years ago

Denali Therapeutics Press release: Study Result


Denali Therapeutics Slides: Study Result

Jun 20, 2023, 8:30 AM EDT - 3 years ago

Denali Therapeutics Slides: Study Result


Denali Therapeutics Quarterly report: Q1 2023

May 8, 2023, 4:00 PM EDT - 3 years ago

Denali Therapeutics Quarterly report: Q1 2023


Denali Therapeutics Earnings release: Q1 2023

May 8, 2023, 4:00 PM EDT - 3 years ago

Denali Therapeutics Earnings release: Q1 2023


Denali Therapeutics Proxy statement: Proxy Filing

Apr 18, 2023, 8:00 AM EDT - 3 years ago

Denali Therapeutics Proxy statement: Proxy Filing


Denali Therapeutics Proxy statement: Proxy Filing

Apr 18, 2023, 8:00 AM EDT - 3 years ago

Denali Therapeutics Proxy statement: Proxy Filing


steven1x
steven1x Aug. 18 at 6:24 PM
$DNLI what did AI miss? https://g.co/gemini/share/60e24f1bed3e
0 · Reply
Estimize
Estimize Aug. 13 at 8:03 PM
Wall St is expecting -0.39 EPS for $DNLI Q3 [Reporting 11/11 AMC] http://www.estimize.com/intro/dnli?chart=historical&metric_name=eps&utm_c
0 · Reply
GoAt2OG
GoAt2OG Aug. 13 at 2:47 PM
$DNLI started off with 750 commons here; let’s see how this moves along
0 · Reply
GoAt2OG
GoAt2OG Aug. 13 at 11:12 AM
$DNLI looking to start a position here; fishing 🎣
0 · Reply
prismmarketview
prismmarketview Aug. 10 at 1:34 PM
(NASDAQ: $DNLI ) Denali Therapeutics believes improving how medicines are delivered across the blood-brain barrier could unlock better outcomes in Alzheimer's disease. With two clinical-stage Alzheimer's programs now advancing and initial human data expected in 2027, investors are increasingly watching whether Denali's proprietary TransportVehicle™ platform can translate promising science into clinical results. https://prismmarketview.com/denali-bets-better-brain-distribution-could-shape-the-next-generation-of-alzheimers-therapies/
0 · Reply
stockpicker63
stockpicker63 Aug. 9 at 3:11 PM
$DNLI — TA + AI Analysis (Short-Term Bullish Setup)
0 · Reply
dgbio
dgbio Aug. 7 at 1:41 AM
$DNLI Orphan Drug designation just received for the FTD-GRN program.
0 · Reply
dgbio
dgbio Aug. 7 at 12:30 AM
$DNLI Guidance for Q3 revenue is 10-12 million, 2x consensus of 5.5 million.
0 · Reply
JFDI
JFDI Aug. 6 at 11:04 PM
$DNLI Weekly base
0 · Reply
EarningsInsider
EarningsInsider Aug. 6 at 10:01 PM
https://www.marketbeat.com/earnings/reports/2026-8-6-denali-therapeutics-inc-stock/ $DNLI Denali Therapeutics Earnings Transcript
0 · Reply
StocktwitsEarnings
StocktwitsEarnings Aug. 6 at 8:13 PM
$DNLI Q2 '26 Earnings Results & Recap • Reported GAAP EPS of -$0.68 up 5.56% YoY • Reported revenue of $3.6M
0 · Reply
Jh900
Jh900 Aug. 6 at 3:21 PM
$DNLI earnings .. what are we saying ?
0 · Reply
Tadstonk
Tadstonk Aug. 3 at 3:05 PM
$DNLI Received Orphan designation for FTD/progranulan
0 · Reply
Merlintrader
Merlintrader Jul. 25 at 1:34 PM
0 · Reply
B2iDigital
B2iDigital Jul. 24 at 9:57 PM
eXoZymes (Nasdaq: $EXOZ ) is among the first projects selected for the inaugural U.S. Department of Energy (DOE) Genesis Mission, a nationwide initiative bringing together national laboratories, universities, companies, and nonprofit organizations to accelerate scientific discovery. eXoZymes will work with Lawrence Berkeley National Laboratory to build AI-powered digital twins for its cell-free biomanufacturing platform. eXoZymes is a B2i Digital Featured Company. See the company’s profile at https://b2idigital.com/exozymes The project extends the company’s AI work from enzyme engineering into manufacturing: • With Berkeley Lab, eXoZymes will develop hybrid digital twins that combine enzyme kinetics, reactor physics, and machine learning to identify optimal operating conditions before lab validation • The award provides access to the DOE Genesis Mission Platform: advanced AI models, AI agents, and high-performance computing • Subject to DOE award negotiations, the project is expected to carry about $747,000 in total funding, including about $147,000 for eXoZymes “We believe the next generation of biomanufacturing will be built at the intersection of artificial intelligence and digital insights into biology,” said Michael Heltzen, Chief Executive Officer of eXoZymes. Read the full release: https://exozymes.com/blog/genesis-mission-2026 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital’s practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
G101SPM
G101SPM Jul. 24 at 2:12 PM
#SHOWTIME International AIDS Conference (July 27-31) Scheduled to appear: $MRK BTIG Biotechnology Conference (July 27) Scheduled to appear: $DNLI, $MLTX, $PCVX
0 · Reply
Quantumup
Quantumup Jul. 23 at 6:44 PM
Morgan Stanley, in a broad research note earnings preview, ⬆️ $ASND to $275 from $256, reiterated (reit'd) Overweight; $DNLI to $36 from $35, reit'd Overweight; $EXEL to $53 from $50, reit'd Equal Weight; and $INCY to $104 from $103, reit'd Equal Weight, and said 2Q26 earnings should reinforce a shift from macro-driven trading toward stock-specific execution and differentiation.
0 · Reply
B2iDigital
B2iDigital Jul. 23 at 4:01 PM
eXoZymes (Nasdaq: $EXOZ ) frames itself as a repeatable engine for unlocking molecule classes. In a Webull webinar, Chief Commercial Officer Damien Perriman put cannabinoids forward as the next class after NCT. eXoZymes Inc. is a B2i Digital Featured Company. See the company's profile at https://b2idigital.com/exozymes-1 "This is not a single product company. It's a repeatable system for unlocking entire classes of molecules," Perryman told investors. Also from the presentation: • NCT is the first proof point and cannabinoids are the second, with cannabinoid receptors present on nearly every cell in the body • That reach spans metabolic, inflammatory, and neurological conditions, where access to rare cannabinoids has long been the bottleneck • eXoZymes says it can now produce rare and entirely new cannabinoids without intoxicating components, optimized toward specific therapeutic objectives Watch the full webinar: https://youtu.be/OmH3TaaMT20 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital's practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
Merlintrader
Merlintrader Jul. 20 at 8:25 PM
Priority Review Voucher explainer: $RCKT and $DNLI turned one FDA approval into $180-205M cash. Relevant for $XBI and $IBB biotech investors. https://www.merlintrader.com/priority-review-voucher-explained-rckt-dnli-2026/
0 · Reply
B2iDigital
B2iDigital Jul. 17 at 9:10 PM
A platform that works in the lab is not yet a business. In a Webull webinar, eXoZymes (Nasdaq: $EXOZ ) pointed to a scale-up run it says clears that bar. eXoZymes Inc. is a B2i Digital Featured Company. See the company's profile at https://b2idigital.com/exozymes-1 Perryman framed the milestone directly: "Many technologies work in the lab, but many also fail at scale. What we've demonstrated here is that the system translates from concept to industrial conditions, and that's what turns this from a science into a viable business." The webinar detailed the run: • The company ran a 100-liter pilot at the end of last year, reporting 99% conversion of raw material to target product and 99.6% purity • The run took place at a third party after eXoZymes tech-transferred its process, operating conditions, and enzyme cascades • Management called this an operational process rather than a theoretical one, and an inflection point for investors Watch the full webinar: https://youtu.be/OmH3TaaMT20 eXoZymes Inc. is a Los Angeles, California based biotechnology company developing cell-free biomanufacturing technology that uses AI-engineered enzymes to convert feedstocks into high-value compounds, with applications across nutraceuticals and pharmaceuticals. Learn more at https://exozymes.com. Discover more emerging growth Featured Companies, industry-leading Featured Experts, and upcoming Featured Conferences at https://b2idigital.com. Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital's practice of investing alongside its Featured Companies. See the complete Disclosure at https://b2idigital.com/disclaimer. B2i Digital is not a broker-dealer or investment adviser. This post is informational and not an offer or solicitation regarding any security. $DNLI, $TWST, $DNA, $ARKG
1 · Reply
IN0V8
IN0V8 Jul. 16 at 2:38 PM
$DNLI Opportunity Deutsche Bank raises target price to $35 from $31
0 · Reply
_ivan
_ivan Jul. 16 at 6:48 AM
0 · Reply