Market Cap 5.25B
Revenue (ttm) 1.00B
Net Income (ttm) 22.39M
EPS (ttm) N/A
PE Ratio 40.23
Forward PE N/A
Profit Margin 2.23%
Debt to Equity Ratio 1.10
Volume 7,931,600
Avg Vol 6,040,128
Day's Range N/A - N/A
Shares Out 128.02M
Stochastic %K 62%
Beta -0.24
Analysts Sell
Price Target $40.12

Company Profile

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops EMPAVELI to treat C3 glomerulopathy and immune complex membranoproli...

Industry: Biotechnology
Sector: Healthcare
Phone: 617 977 5700
Website: apellis.com
Address:
100 Fifth Avenue, Waltham, United States
Mergerbrief
Mergerbrief May. 13 at 12:16 PM
$APLS / $BIIB – Tender Offer Expires @ Midnight
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech May. 10 at 3:59 PM
$ACAD enterprise value is 0.40X 5-year analyst consensus revenue estimates. The attachment notes the actual 5-year M&A multiples paid in 11 commercial-stage exits. These 11 peers, all projected to do over $750MM in sales in the year following acquisition just like ACAD, were acquired for 0.86 to 1.25X 5-year revenue forecasts (some even higher). Because ACAD's multiples reflect enterprise value, the relationship to market cap is not linear as ACAD's 3/31/26 cash is $859MM The 2nd attachment shows ACAD's fully diluted market cap & enterprise value at $22.40 per share & a hypothetical $46.40 M&A share price if ACAD was acquired for 1.0X 5-year sales, EXCLUDING FY26 GRANTS. We'd remind investors that $APLS closed at $17.07 per share the day before Biogen announced the acquisition for $41 This is not investment advice. The attachments are simple "what-ifs." We have no idea what ACAD might be worth in a M&A exit.
1 · Reply
TwongStocks
TwongStocks May. 7 at 6:03 PM
$APLS Equity Corporate Actions Alert #2026 - 310 Information Regarding the Tender Offer of Apellis Pharmaceuticals, Inc. (APLS) https://www.nasdaqtrader.com/TraderNews.aspx?id=ECA2026-310 The tender offer by Biogen Inc. $BIIB to acquire all of the outstanding common stock of Apellis Pharmaceuticals, Inc. $APLS is scheduled to expire at 11:59 p.m. ET, on May 13, 2026, unless extended or terminated. The subsequent merger is tentatively scheduled to close prior to the market open on May 14, 2026. In anticipation of the closing, the stock will be halted immediately following the after-hours session at or around 7:50 p.m. on May 13, 2026. If the merger closes as planned, the stock will remain halted on the day of closing (May 14th) and will be suspended effective May 15, 2026. APLS shareholders will get $41.00 per share plus a non-transferable contingent value right (CVR).
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech May. 7 at 6:03 PM
$CPRX M&A valuation as multiples of Year 4 (FY29), 5-year & 10-year revenue estimates versus peer commercial-stage biopharma M&A exits. Peer multiples are calculated using the revenue forecasts prepared by the management/BOD of the acquiree. $KALV & $APLS also use analyst consensus. NOTE CPRX is being acquired at one of the highest 10-year multiples (very likely because CPRX is a much more mature commercial-stage bio versus most of the peers). We're merely sharing our analysis. This is not investment advice. We cannot think of any peer like CPRX (that sold multiple therapies) except for $XERS which has patent life considerations $XBI
4 · Reply
StocktwitsEarnings
StocktwitsEarnings May. 7 at 11:05 AM
$APLS Q1 '26 Earnings Results & Recap • Reported GAAP EPS of $0.15 up 120.27% YoY • Reported revenue of $268.3M up 60.85% YoY
0 · Reply
JFais
JFais Apr. 30 at 7:58 PM
$OMER (L) When they did the zaltenibart deal in October, it gave them a lifeline as no one knew if narsoplimab would get approved in TA-TMA Also, bear commentary= slow launch out of the gate (so far, formulary wins exceeding expectations) I imagine $NVO would love to take Yartemlea into expansion indications (ARDS & other endothelial injury-related disorders), also continue building out its nephrology presence... *Though $BIIB could be another interested party after digesting $APLS
2 · Reply
SuperGreenToday
SuperGreenToday Apr. 29 at 11:11 PM
$APLS Share Price: $40.97 Contract Selected: Oct 16, 2026 $40 Calls Buy Zone: $0.85 – $1.05 Target Zone: $1.37 – $1.67 Potential Upside: 52% ROI Time to Expiration: 169 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
JFais
JFais Apr. 24 at 12:17 PM
Reminder some DCA purchases work out well, others not so much $APLS $BHVN $DERM
1 · Reply
JFais
JFais Apr. 23 at 12:37 PM
Eventful Week: -Redeployed rest of $APLS buyout proceeds -Shared DD on a new commercial setup -Published April Playbook this morning (potential names on radar for future purchase, I continually prioritize these based on actionability & which has most favorable r/r) -Coffee at the Close call Friday $XBI
0 · Reply
JFais
JFais Apr. 22 at 7:32 PM
$APLS- all out, may the boring base hits (& occasional homerun) continue
0 · Reply
Latest News on APLS
Apellis price target raised to $41 from $21 at RBC Capital

2026-04-07T15:04:57.000Z - 5 weeks ago

Apellis price target raised to $41 from $21 at RBC Capital


Apellis price target raised to $41 from $20 at Mizuho

2026-04-02T11:24:04.000Z - 5 weeks ago

Apellis price target raised to $41 from $20 at Mizuho


Apellis downgraded to Neutral from Buy at Roth Capital

2026-04-02T08:31:01.000Z - 5 weeks ago

Apellis downgraded to Neutral from Buy at Roth Capital


Biogen price target raised to $275 from $250 at Oppenheimer

2026-04-01T12:07:17.000Z - 6 weeks ago

Biogen price target raised to $275 from $250 at Oppenheimer

BIIB


Apellis downgraded to Neutral from Buy at H.C. Wainwright

2026-04-01T10:12:20.000Z - 6 weeks ago

Apellis downgraded to Neutral from Buy at H.C. Wainwright


Apellis downgraded to Neutral from Overweight at JPMorgan

2026-04-01T09:41:53.000Z - 6 weeks ago

Apellis downgraded to Neutral from Overweight at JPMorgan


Apellis downgraded to Hold from Buy at Stifel

2026-03-31T20:41:21.000Z - 6 weeks ago

Apellis downgraded to Hold from Buy at Stifel


Apellis downgraded to Neutral from Buy at Citi

2026-03-31T20:22:12.000Z - 6 weeks ago

Apellis downgraded to Neutral from Buy at Citi

BIIB


Apellis downgraded to Hold from Buy at Jefferies

2026-03-31T17:15:59.000Z - 6 weeks ago

Apellis downgraded to Hold from Buy at Jefferies

BIIB


Why This Pharma Stock More Than Doubled Today

Mar 31, 2026, 9:41 AM EDT - 6 weeks ago

Why This Pharma Stock More Than Doubled Today

BIIB


Biogen to Acquire Apellis Pharmaceuticals for $5.6 Billion

Mar 31, 2026, 7:44 AM EDT - 6 weeks ago

Biogen to Acquire Apellis Pharmaceuticals for $5.6 Billion

BIIB


Biogen to buy Apellis Pharmaceuticals for $5.6 billion

Mar 31, 2026, 7:05 AM EDT - 6 weeks ago

Biogen to buy Apellis Pharmaceuticals for $5.6 billion

BIIB


Apellis Pharmaceuticals Earnings Call Transcript: Q4 2025

Feb 24, 2026, 8:30 AM EST - 2 months ago

Apellis Pharmaceuticals Earnings Call Transcript: Q4 2025


Apellis Pharmaceuticals Earnings Call Transcript: Q3 2025

Oct 30, 2025, 8:30 AM EDT - 6 months ago

Apellis Pharmaceuticals Earnings Call Transcript: Q3 2025


Apellis Pharmaceuticals Earnings Call Transcript: Q2 2025

Jul 31, 2025, 8:30 AM EDT - 10 months ago

Apellis Pharmaceuticals Earnings Call Transcript: Q2 2025


Apellis Pharmaceuticals Transcript: Study Update

Jul 29, 2025, 8:00 AM EDT - 10 months ago

Apellis Pharmaceuticals Transcript: Study Update


Apellis Pharmaceuticals Earnings Call Transcript: Q1 2025

May 7, 2025, 8:30 AM EDT - 1 year ago

Apellis Pharmaceuticals Earnings Call Transcript: Q1 2025


Apellis Pharmaceuticals Earnings Call Transcript: Q4 2024

Feb 28, 2025, 8:30 AM EST - 1 year ago

Apellis Pharmaceuticals Earnings Call Transcript: Q4 2024


Mergerbrief
Mergerbrief May. 13 at 12:16 PM
$APLS / $BIIB – Tender Offer Expires @ Midnight
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech May. 10 at 3:59 PM
$ACAD enterprise value is 0.40X 5-year analyst consensus revenue estimates. The attachment notes the actual 5-year M&A multiples paid in 11 commercial-stage exits. These 11 peers, all projected to do over $750MM in sales in the year following acquisition just like ACAD, were acquired for 0.86 to 1.25X 5-year revenue forecasts (some even higher). Because ACAD's multiples reflect enterprise value, the relationship to market cap is not linear as ACAD's 3/31/26 cash is $859MM The 2nd attachment shows ACAD's fully diluted market cap & enterprise value at $22.40 per share & a hypothetical $46.40 M&A share price if ACAD was acquired for 1.0X 5-year sales, EXCLUDING FY26 GRANTS. We'd remind investors that $APLS closed at $17.07 per share the day before Biogen announced the acquisition for $41 This is not investment advice. The attachments are simple "what-ifs." We have no idea what ACAD might be worth in a M&A exit.
1 · Reply
TwongStocks
TwongStocks May. 7 at 6:03 PM
$APLS Equity Corporate Actions Alert #2026 - 310 Information Regarding the Tender Offer of Apellis Pharmaceuticals, Inc. (APLS) https://www.nasdaqtrader.com/TraderNews.aspx?id=ECA2026-310 The tender offer by Biogen Inc. $BIIB to acquire all of the outstanding common stock of Apellis Pharmaceuticals, Inc. $APLS is scheduled to expire at 11:59 p.m. ET, on May 13, 2026, unless extended or terminated. The subsequent merger is tentatively scheduled to close prior to the market open on May 14, 2026. In anticipation of the closing, the stock will be halted immediately following the after-hours session at or around 7:50 p.m. on May 13, 2026. If the merger closes as planned, the stock will remain halted on the day of closing (May 14th) and will be suspended effective May 15, 2026. APLS shareholders will get $41.00 per share plus a non-transferable contingent value right (CVR).
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech May. 7 at 6:03 PM
$CPRX M&A valuation as multiples of Year 4 (FY29), 5-year & 10-year revenue estimates versus peer commercial-stage biopharma M&A exits. Peer multiples are calculated using the revenue forecasts prepared by the management/BOD of the acquiree. $KALV & $APLS also use analyst consensus. NOTE CPRX is being acquired at one of the highest 10-year multiples (very likely because CPRX is a much more mature commercial-stage bio versus most of the peers). We're merely sharing our analysis. This is not investment advice. We cannot think of any peer like CPRX (that sold multiple therapies) except for $XERS which has patent life considerations $XBI
4 · Reply
StocktwitsEarnings
StocktwitsEarnings May. 7 at 11:05 AM
$APLS Q1 '26 Earnings Results & Recap • Reported GAAP EPS of $0.15 up 120.27% YoY • Reported revenue of $268.3M up 60.85% YoY
0 · Reply
JFais
JFais Apr. 30 at 7:58 PM
$OMER (L) When they did the zaltenibart deal in October, it gave them a lifeline as no one knew if narsoplimab would get approved in TA-TMA Also, bear commentary= slow launch out of the gate (so far, formulary wins exceeding expectations) I imagine $NVO would love to take Yartemlea into expansion indications (ARDS & other endothelial injury-related disorders), also continue building out its nephrology presence... *Though $BIIB could be another interested party after digesting $APLS
2 · Reply
SuperGreenToday
SuperGreenToday Apr. 29 at 11:11 PM
$APLS Share Price: $40.97 Contract Selected: Oct 16, 2026 $40 Calls Buy Zone: $0.85 – $1.05 Target Zone: $1.37 – $1.67 Potential Upside: 52% ROI Time to Expiration: 169 Days | Updates via https://fxcapta.com/stockinfo/
0 · Reply
JFais
JFais Apr. 24 at 12:17 PM
Reminder some DCA purchases work out well, others not so much $APLS $BHVN $DERM
1 · Reply
JFais
JFais Apr. 23 at 12:37 PM
Eventful Week: -Redeployed rest of $APLS buyout proceeds -Shared DD on a new commercial setup -Published April Playbook this morning (potential names on radar for future purchase, I continually prioritize these based on actionability & which has most favorable r/r) -Coffee at the Close call Friday $XBI
0 · Reply
JFais
JFais Apr. 22 at 7:32 PM
$APLS- all out, may the boring base hits (& occasional homerun) continue
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Apr. 19 at 4:53 PM
$TARS valuation, analyst consensus & related revenue multiples versus actual M&A revenue multiples paid to acquire $FOLD & $APLS Analysts project TARS to generate more revenues over the next 5 & 9 years than FOLD. FOLD was acquired for an enterprise value of $4.8B. Analysts project TARS to generate slightly lower revenues over the next 5 & 9 years than APLS. APLS was acquired for an enterprise value of $5.6B. If analysts project TARS revenues to be in between FOLD & APLS, does that suggest TARS' hypothetical M&A enterprise value would be somewhere in between the 2. TARS revenues generate higher gross margins than both FOLD & APLS. Does this suggest TARS would (again hypothetically) command a higher M&A exit multiple? We're curious what genuine TARS investors believe. $XBI $IBB
1 · Reply
anachartanalyst
anachartanalyst Apr. 17 at 3:02 PM
$APLS https://anachart.com/wp-content/uploads/ana_temp/1776438120_soc-img.jpg
0 · Reply
JFais
JFais Apr. 16 at 1:21 PM
$TVTX- had to rain on the parade didn't you @adamfeuerstein 😉 Good news $TVTX will build out the FSGS market and better treatments will follow (CCR2 blocker DMX-200 & complement inhibitors like $APLS $BIIB Empaveli in P3, BAFF APRIL a la atacicept & $VRTX poveticacicept, etc)
0 · Reply
Pharmer23
Pharmer23 Apr. 10 at 1:08 PM
$SRPT I was in $APLS FOR AGES . Vasculitis scare and stock tanked from almost 90 and stayed shit for years . Out of no where but out with 140 percent premium . Don’t be an idiot thinking this will be 20 bucks forever . Too much going on , especially now these arrowhead assets showed some serious potential . BP will want to get this cheap . PMOS are not going anywhere btw . Exondys reslly has no risk near term . The other two still won’t get pulled . They’re still being prescribed at over 90 % retention . Why would prescribers give something to these poor kids for 10 years if it was shit an didn’t work ? Elevidys data shows slowing of disease a suspect will only get better at year 4.5,6 etc . There’s too much going do this to stay here in the 20s
2 · Reply
JFais
JFais Apr. 9 at 11:31 PM
Put 14%pw of $APLS profits to work (sooner than I'd planned) - working on the remaining 6%pw (no rush, would prefer a pullback but again each day's a blank slate to look at current r/r)
0 · Reply
RunnerSignals
RunnerSignals Apr. 7 at 3:26 PM
$CAR $SSL $APLS $AA $ELVN highs are printing but volume not confirming across the board
0 · Reply
JFais
JFais Apr. 7 at 1:33 PM
$TLX has risen to my #2 position after $APLS (still redeploying buyout proceeds) Encouraging Q1 report today (gaining share in PSMA diagnostic market + growing uptake for Gozellix) Follow it up with Pixclara & Zircaix approvals later this year (or 1H 27) => improving sentiment
0 · Reply
monoksop
monoksop Apr. 6 at 2:05 PM
$APLS I have a feeling this will hit $41 in the next couple of months.
0 · Reply
CapitalMonk
CapitalMonk Apr. 6 at 11:21 AM
$APLS Price: $40.41 (+0.05%) Trend: Bearish Market Bias (7D): Bearish Bias 📉 Expected Range: ±9.43% RSI: 89.4 | Momentum: Strong Momentum Volume: +20.9% vs avg Volatility: 30.55% Support: $16.83 | Resistance: $40.48 Tools used: https://www.trade-ideas.com Code: INTERSTOCK25
1 · Reply
Grimy4828
Grimy4828 Apr. 6 at 8:57 AM
$APLS 😂
0 · Reply
PaulLaurent
PaulLaurent Apr. 4 at 6:20 PM
🚀📈 Top Gainers 📈🚀 Last Week $GVH $SST $SKYQ $APLS $BFRG
0 · Reply
Night_Owl_Biotech
Night_Owl_Biotech Apr. 4 at 5:16 PM
88% of comm'l-stage non-oncology focused bios that sell within 33 months of FDA approval are sold at meaningful gains for shareholders (versus their closing share price 2 days post approval). Only 11% of bios in this peer group sold 33 months post approval are sold at gains. The $APLS exit is consistent with this phenomenon. Empaveli was first approved on Friday 5/14/21. Had you acquired APLS shares 2 full trading days later (once settled), you would have paid $51.31 per share. $BIIB is buying APLS for $41.00 per share (plus a $2.00 CVR). Hence investors who acquired & held APLS over this period are down roughly 23% over the last 59 months. The phenomenon is the same in oncology except the window is 24 months (exactly 2 years). $IOVA just eclipsed 2 years. The evidence is overwhelming shareholder value is maximized via M&A exit within 2-3 years post approval $TARS is nearing 33 months (but will likely be an exception). It closed at $19.87 at approval +2 $CRMD ? This is not investment advice
3 · Reply